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Preclinical pharmacology and toxicology of intravenous MV-NIS, an oncolytic measles virus administered with or without cyclophosphamide.
Myers RM, Greiner SM, Harvey ME, Griesmann G, Kuffel MJ, Buhrow SA, Reid JM, Federspiel M, Ames MM, Dingli D, Schweikart K, Welch A, Dispenzieri A, Peng KW, Russell SJ. Myers RM, et al. Among authors: greiner sm. Clin Pharmacol Ther. 2007 Dec;82(6):700-10. doi: 10.1038/sj.clpt.6100409. Epub 2007 Oct 31. Clin Pharmacol Ther. 2007. PMID: 17971816 Free PMC article.
Toxicology study of repeat intracerebral administration of a measles virus derivative producing carcinoembryonic antigen in rhesus macaques in support of a phase I/II clinical trial for patients with recurrent gliomas.
Myers R, Harvey M, Kaufmann TJ, Greiner SM, Krempski JW, Raffel C, Shelton SE, Soeffker D, Zollman P, Federspiel MJ, Blanco M, Galanis E. Myers R, et al. Hum Gene Ther. 2008 Jul;19(7):690-8. doi: 10.1089/hum.2008.035. Hum Gene Ther. 2008. PMID: 18576918 Free PMC article.
We have previously demonstrated that oncolytic measles virus strains derived from the Edmonston vaccine lineage have significant antitumor activity against gliomas [Phuong, L.K., Allen, C., Peng, K.W., Giannini, C., Greiner, S., Teneyck, C.J., Mishra, P.K., Macura, …
We have previously demonstrated that oncolytic measles virus strains derived from the Edmonston vaccine lineage have significant antitumor a …
Safety studies on intrahepatic or intratumoral injection of oncolytic vesicular stomatitis virus expressing interferon-beta in rodents and nonhuman primates.
Jenks N, Myers R, Greiner SM, Thompson J, Mader EK, Greenslade A, Griesmann GE, Federspiel MJ, Rakela J, Borad MJ, Vile RG, Barber GN, Meier TR, Blanco MC, Carlson SK, Russell SJ, Peng KW. Jenks N, et al. Hum Gene Ther. 2010 Apr;21(4):451-62. doi: 10.1089/hum.2009.111. Hum Gene Ther. 2010. PMID: 19911974 Free PMC article.
243 results