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Ceragenins exhibit antiviral activity against SARS-CoV-2 by increasing the expression and release of type I interferons upon activation of the host's immune response.
Suprewicz Ł, Szczepański A, Lenart M, Piktel E, Fiedoruk K, Barreto-Duran E, Kula-Pacurar A, Savage PB, Milewska A, Bucki R, Pyrć K. Suprewicz Ł, et al. Among authors: pyrc k. Antiviral Res. 2023 Sep;217:105676. doi: 10.1016/j.antiviral.2023.105676. Epub 2023 Jul 20. Antiviral Res. 2023. PMID: 37481038
Reversible rearrangement of the cellular cytoskeleton: A key to the broad-spectrum antiviral activity of novel amphiphilic polymers.
Dabrowska A, Botwina P, Barreto-Duran E, Kubisiak A, Obloza M, Synowiec A, Szczepanski A, Targosz-Korecka M, Szczubialka K, Nowakowska M, Pyrc K. Dabrowska A, et al. Among authors: pyrc k. Mater Today Bio. 2023 Aug 7;22:100763. doi: 10.1016/j.mtbio.2023.100763. eCollection 2023 Oct. Mater Today Bio. 2023. PMID: 37600352 Free PMC article.
Novel inhibitors of HSV-1 protease effective in vitro and in vivo.
Pachota M, Grzywa R, Iwanejko J, Synowiec A, Iwan D, Kamińska K, Skoreński M, Bielecka E, Szczubiałka K, Nowakowska M, Mackereth CD, Wojaczyńska E, Sieńczyk M, Pyrć K. Pachota M, et al. Among authors: pyrc k. Antiviral Res. 2023 May;213:105604. doi: 10.1016/j.antiviral.2023.105604. Epub 2023 Apr 11. Antiviral Res. 2023. PMID: 37054954 Free article.
SARS-CoV-2 infection impairs NK cell functions via activation of the LLT1-CD161 axis.
Lenart M, Górecka M, Bochenek M, Barreto-Duran E, Szczepański A, Gałuszka-Bulaga A, Mazur-Panasiuk N, Węglarczyk K, Siwiec-Koźlik A, Korkosz M, Łabaj PP, Baj-Krzyworzeka M, Siedlar M, Pyrc K. Lenart M, et al. Among authors: pyrc k. Front Immunol. 2023 May 23;14:1123155. doi: 10.3389/fimmu.2023.1123155. eCollection 2023. Front Immunol. 2023. PMID: 37287972 Free PMC article.
130 results