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Downregulation of KLF6 is an early event in hepatocarcinogenesis, and stimulates proliferation while reducing differentiation.
Kremer-Tal S, Narla G, Chen Y, Hod E, DiFeo A, Yea S, Lee JS, Schwartz M, Thung SN, Fiel IM, Banck M, Zimran E, Thorgeirsson SS, Mazzaferro V, Bruix J, Martignetti JA, Llovet JM, Friedman SL. Kremer-Tal S, et al. Among authors: thorgeirsson ss. J Hepatol. 2007 Apr;46(4):645-54. doi: 10.1016/j.jhep.2006.10.012. Epub 2006 Nov 27. J Hepatol. 2007. PMID: 17196295 Free PMC article.
Functional genomics of hepatocellular carcinoma.
Thorgeirsson SS, Lee JS, Grisham JW. Thorgeirsson SS, et al. Hepatology. 2006 Feb;43(2 Suppl 1):S145-50. doi: 10.1002/hep.21063. Hepatology. 2006. PMID: 16447291 Review.
Genetic profiling of human hepatocellular carcinoma.
Lee JS, Thorgeirsson SS. Lee JS, et al. Among authors: thorgeirsson ss. Semin Liver Dis. 2005;25(2):125-32. doi: 10.1055/s-2005-871192. Semin Liver Dis. 2005. PMID: 15918141 Review.
Sulfatase 2 up-regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinoma.
Lai JP, Sandhu DS, Yu C, Han T, Moser CD, Jackson KK, Guerrero RB, Aderca I, Isomoto H, Garrity-Park MM, Zou H, Shire AM, Nagorney DM, Sanderson SO, Adjei AA, Lee JS, Thorgeirsson SS, Roberts LR. Lai JP, et al. Among authors: thorgeirsson ss. Hepatology. 2008 Apr;47(4):1211-22. doi: 10.1002/hep.22202. Hepatology. 2008. PMID: 18318435 Free PMC article.
515 results