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FcγRIIb on myeloid cells rather than on B cells protects from collagen-induced arthritis.
Yilmaz-Elis AS, Ramirez JM, Asmawidjaja P, van der Kaa J, Mus AM, Brem MD, Claassens JW, Breukel C, Brouwers C, Mangsbo SM, Boross P, Lubberts E, Verbeek JS. Yilmaz-Elis AS, et al. Among authors: asmawidjaja p. J Immunol. 2014 Jun 15;192(12):5540-7. doi: 10.4049/jimmunol.1303272. Epub 2014 May 19. J Immunol. 2014. PMID: 24842758
Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin-17A production.
van Hamburg JP, Asmawidjaja PS, Davelaar N, Mus AM, Colin EM, Hazes JM, Dolhain RJ, Lubberts E. van Hamburg JP, et al. Among authors: asmawidjaja ps. Arthritis Rheum. 2011 Jan;63(1):73-83. doi: 10.1002/art.30093. Arthritis Rheum. 2011. PMID: 20954258 Free article.
TNF blockade requires 1,25(OH)2D3 to control human Th17-mediated synovial inflammation.
van Hamburg JP, Asmawidjaja PS, Davelaar N, Mus AM, Cornelissen F, van Leeuwen JP, Hazes JM, Dolhain RJ, Bakx PA, Colin EM, Lubberts E. van Hamburg JP, et al. Among authors: asmawidjaja ps. Ann Rheum Dis. 2012 Apr;71(4):606-12. doi: 10.1136/annrheumdis-2011-200424. Epub 2012 Jan 4. Ann Rheum Dis. 2012. PMID: 22219138
IL-17/Th17 mediated synovial inflammation is IL-22 independent.
van Hamburg JP, Corneth OB, Paulissen SM, Davelaar N, Asmawidjaja PS, Mus AM, Lubberts E. van Hamburg JP, et al. Ann Rheum Dis. 2013 Oct;72(10):1700-7. doi: 10.1136/annrheumdis-2012-202373. Epub 2013 Jan 17. Ann Rheum Dis. 2013. PMID: 23328939
Loss of IL-22 inhibits autoantibody formation in collagen-induced arthritis in mice.
Corneth OB, Reijmers RM, Mus AM, Asmawidjaja PS, van Hamburg JP, Papazian N, Siegers JY, Mourcin F, Amin R, Tarte K, Hendriks RW, Cupedo T, Lubberts E. Corneth OB, et al. Eur J Immunol. 2016 Jun;46(6):1404-14. doi: 10.1002/eji.201546241. Epub 2016 May 12. Eur J Immunol. 2016. PMID: 27067635 Free article.
1,25(OH)2D3 and dexamethasone additively suppress synovial fibroblast activation by CCR6+ T helper memory cells and enhance the effect of tumor necrosis factor alpha blockade.
Dankers W, González-Leal C, Davelaar N, Asmawidjaja PS, Mus AMC, Hazes JMW, Colin EM, Lubberts E. Dankers W, et al. Among authors: asmawidjaja ps. Arthritis Res Ther. 2018 Sep 20;20(1):212. doi: 10.1186/s13075-018-1706-9. Arthritis Res Ther. 2018. PMID: 30236152 Free PMC article.
26 results