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Psoriasis-Associated Late Cornified Envelope (LCE) Proteins Have Antibacterial Activity.
Niehues H, Tsoi LC, van der Krieken DA, Jansen PAM, Oortveld MAW, Rodijk-Olthuis D, van Vlijmen IMJJ, Hendriks WJAJ, Helder RW, Bouwstra JA, van den Bogaard EH, Stuart PE, Nair RP, Elder JT, Zeeuwen PLJM, Schalkwijk J. Niehues H, et al. J Invest Dermatol. 2017 Nov;137(11):2380-2388. doi: 10.1016/j.jid.2017.06.003. Epub 2017 Jun 17. J Invest Dermatol. 2017. PMID: 28634035 Free PMC article.
Investigations into the FLG Null Phenotype: Showcasing the Methodology for CRISPR/Cas9 Editing of Human Keratinocytes.
Smits JPH, van den Brink NJM, Meesters LD, Hamdaoui H, Niehues H, Jansen PAM, van Vlijmen-Willems IMJJ, Rodijk-Olthuis D, Evrard C, Poumay Y, van Geel M, Hendriks WJAJ, Schalkwijk J, Zeeuwen PLJM, van den Bogaard EH. Smits JPH, et al. J Invest Dermatol. 2023 Aug;143(8):1520-1528.e5. doi: 10.1016/j.jid.2023.02.021. Epub 2023 Mar 7. J Invest Dermatol. 2023. PMID: 36893939 Free article.
The Effects of Human Beta-Defensins on Skin Cells in vitro.
van Kilsdonk JWJ, Jansen PAM, van den Bogaard EH, Bos C, Bergers M, Zeeuwen PLJM, Schalkwijk J. van Kilsdonk JWJ, et al. Dermatology. 2017;233(2-3):155-163. doi: 10.1159/000477346. Epub 2017 Jul 8. Dermatology. 2017. PMID: 28689201
Beta-defensin-2 protein is a serum biomarker for disease activity in psoriasis and reaches biologically relevant concentrations in lesional skin.
Jansen PA, Rodijk-Olthuis D, Hollox EJ, Kamsteeg M, Tjabringa GS, de Jongh GJ, van Vlijmen-Willems IM, Bergboer JG, van Rossum MM, de Jong EM, den Heijer M, Evers AW, Bergers M, Armour JA, Zeeuwen PL, Schalkwijk J. Jansen PA, et al. PLoS One. 2009;4(3):e4725. doi: 10.1371/journal.pone.0004725. Epub 2009 Mar 6. PLoS One. 2009. PMID: 19266104 Free PMC article.
243 results