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Substituted thiophene-anthranilamides as potent inhibitors of human factor Xa.
Bioorg Med Chem. 2007 Mar 1;15(5):2127-46. doi: 10.1016/j.bmc.2006.12.019. Epub 2006 Dec 13.
Bioorg Med Chem. 2007.
PMID: 17227710
Structure-activity relationships of substituted benzothiophene-anthranilamide factor Xa inhibitors.
Chou YL, Davey DD, Eagen KA, Griedel BD, Karanjawala R, Phillips GB, Sacchi KL, Shaw KJ, Wu SC, Lentz D, Liang AM, Trinh L, Morrissey MM, Kochanny MJ.
Chou YL, et al. Among authors: karanjawala r.
Bioorg Med Chem Lett. 2003 Feb 10;13(3):507-11. doi: 10.1016/s0960-894x(02)00938-1.
Bioorg Med Chem Lett. 2003.
PMID: 12565961
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Synthesis and biological evaluation of piperazine-based derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1).
Ye B, Chou YL, Karanjawala R, Lee W, Lu SF, Shaw KJ, Jones S, Lentz D, Liang A, Tseng JL, Wu Q, Zhao Z.
Ye B, et al. Among authors: karanjawala r.
Bioorg Med Chem Lett. 2004 Feb 9;14(3):761-5. doi: 10.1016/j.bmcl.2003.11.035.
Bioorg Med Chem Lett. 2004.
PMID: 14741285
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Thiophene-anthranilamides as highly potent and orally available factor Xa inhibitors.
Ye B, Arnaiz DO, Chou YL, Griedel BD, Karanjawala R, Lee W, Morrissey MM, Sacchi KL, Sakata ST, Shaw KJ, Wu SC, Zhao Z, Adler M, Cheeseman S, Dole WP, Ewing J, Fitch R, Lentz D, Liang A, Light D, Morser J, Post J, Rumennik G, Subramanyam B, Sullivan ME, Vergona R, Walters J, Wang YX, White KA, Whitlow M, Kochanny MJ.
Ye B, et al. Among authors: karanjawala r.
J Med Chem. 2007 Jun 28;50(13):2967-80. doi: 10.1021/jm070125f. Epub 2007 May 31.
J Med Chem. 2007.
PMID: 17536795
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