Moerke NJ - Search Results

1

Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G.

Moerke NJ, Aktas H, Chen H, Cantel S, Reibarkh MY, Fahmy A, Gross JD, Degterev A, Yuan J, Chorev M, Halperin JA, Wagner G. Moerke NJ, et al. Cell. 2007 Jan 26;128(2):257-67. doi: 10.1016/j.cell.2006.11.046. Cell. 2007. PMID: 17254965 Free article.

2

Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E.

Gross JD, Moerke NJ, von der Haar T, Lugovskoy AA, Sachs AB, McCarthy JE, Wagner G. Gross JD, et al. Among authors: moerke nj. Cell. 2003 Dec 12;115(6):739-50. doi: 10.1016/s0092-8674(03)00975-9. Cell. 2003. PMID: 14675538 Free article.

3

Synthesis of fluorescein labeled 7-methylguanosinemonophosphate.

Natarajan A, Moerke N, Fan YH, Chen H, Christ WJ, Wagner G, Halperin JA. Natarajan A, et al. Bioorg Med Chem Lett. 2004 May 17;14(10):2657-60. doi: 10.1016/j.bmcl.2004.02.090. Bioorg Med Chem Lett. 2004. PMID: 15109672

4

Folding transitions during assembly of the eukaryotic mRNA cap-binding complex.

von der Haar T, Oku Y, Ptushkina M, Moerke N, Wagner G, Gross JD, McCarthy JE. von der Haar T, et al. J Mol Biol. 2006 Mar 3;356(4):982-92. doi: 10.1016/j.jmb.2005.12.034. Epub 2005 Dec 27. J Mol Biol. 2006. PMID: 16405910

5

Inhibition of the interactions between eukaryotic initiation factors 4E and 4G impairs long-term associative memory consolidation but not reconsolidation.

Hoeffer CA, Cowansage KK, Arnold EC, Banko JL, Moerke NJ, Rodriguez R, Schmidt EK, Klosi E, Chorev M, Lloyd RE, Pierre P, Wagner G, LeDoux JE, Klann E. Hoeffer CA, et al. Among authors: moerke nj. Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3383-8. doi: 10.1073/pnas.1013063108. Epub 2011 Feb 2. Proc Natl Acad Sci U S A. 2011. PMID: 21289279 Free PMC article.

6

Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer.

Wei S, Kozono S, Kats L, Nechama M, Li W, Guarnerio J, Luo M, You MH, Yao Y, Kondo A, Hu H, Bozkurt G, Moerke NJ, Cao S, Reschke M, Chen CH, Rego EM, Lo-Coco F, Cantley LC, Lee TH, Wu H, Zhang Y, Pandolfi PP, Zhou XZ, Lu KP. Wei S, et al. Among authors: moerke nj. Nat Med. 2015 May;21(5):457-66. doi: 10.1038/nm.3839. Epub 2015 Apr 13. Nat Med. 2015. PMID: 25849135 Free PMC article.

7

A high-throughput, cell-based screening method for siRNA and small molecule inhibitors of mTORC1 signaling using the In Cell Western technique.

Hoffman GR, Moerke NJ, Hsia M, Shamu CE, Blenis J. Hoffman GR, et al. Among authors: moerke nj. Assay Drug Dev Technol. 2010 Apr;8(2):186-99. doi: 10.1089/adt.2009.0213. Assay Drug Dev Technol. 2010. PMID: 20085456 Free PMC article.

8

Assay Development and High-Throughput Screening for Inhibitors of Kaposi's Sarcoma-Associated Herpesvirus N-Terminal Latency-Associated Nuclear Antigen Binding to Nucleosomes.

Beauchemin C, Moerke NJ, Faloon P, Kaye KM. Beauchemin C, et al. Among authors: moerke nj. J Biomol Screen. 2014 Jul;19(6):947-58. doi: 10.1177/1087057114520973. Epub 2014 Feb 11. J Biomol Screen. 2014. PMID: 24518064 Free PMC article.

9

Differential determinants of cancer cell insensitivity to antimitotic drugs discriminated by a one-step cell imaging assay.

Tang Y, Xie T, Florian S, Moerke N, Shamu C, Benes C, Mitchison TJ. Tang Y, et al. J Biomol Screen. 2013 Oct;18(9):1062-71. doi: 10.1177/1087057113493804. Epub 2013 Jun 20. J Biomol Screen. 2013. PMID: 23788527 Free PMC article.

10

Fluorescence Polarization (FP) Assays for Monitoring Peptide-Protein or Nucleic Acid-Protein Binding.

Moerke NJ. Moerke NJ. Curr Protoc Chem Biol. 2009 Dec 1;1(1):1-15. doi: 10.1002/9780470559277.ch090102. Curr Protoc Chem Biol. 2009. PMID: 23839960

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