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The TREM-1/DAP12 pathway.
Tessarz AS, Cerwenka A. Tessarz AS, et al. Among authors: cerwenka a. Immunol Lett. 2008 Mar 15;116(2):111-6. doi: 10.1016/j.imlet.2007.11.021. Epub 2007 Dec 26. Immunol Lett. 2008. PMID: 18192027 Review.
Btk is a positive regulator in the TREM-1/DAP12 signaling pathway.
Ormsby T, Schlecker E, Ferdin J, Tessarz AS, Angelisová P, Köprülü AD, Borte M, Warnatz K, Schulze I, Ellmeier W, Horejsí V, Cerwenka A. Ormsby T, et al. Among authors: cerwenka a. Blood. 2011 Jul 28;118(4):936-45. doi: 10.1182/blood-2010-11-317016. Epub 2011 Jun 9. Blood. 2011. PMID: 21659545 Free article.
TREM-1 links dyslipidemia to inflammation and lipid deposition in atherosclerosis.
Zysset D, Weber B, Rihs S, Brasseit J, Freigang S, Riether C, Banz Y, Cerwenka A, Simillion C, Marques-Vidal P, Ochsenbein AF, Saurer L, Mueller C. Zysset D, et al. Among authors: cerwenka a. Nat Commun. 2016 Oct 20;7:13151. doi: 10.1038/ncomms13151. Nat Commun. 2016. PMID: 27762264 Free PMC article.
TREM-1 multimerization is essential for its activation on monocytes and neutrophils.
Carrasco K, Boufenzer A, Jolly L, Le Cordier H, Wang G, Heck AJ, Cerwenka A, Vinolo E, Nazabal A, Kriznik A, Launay P, Gibot S, Derive M. Carrasco K, et al. Among authors: cerwenka a. Cell Mol Immunol. 2019 May;16(5):460-472. doi: 10.1038/s41423-018-0003-5. Epub 2018 Mar 22. Cell Mol Immunol. 2019. PMID: 29568119 Free PMC article.
132 results