Waterhouse DN - Search Results

1

Modulation of cancer cell survival pathways using multivalent liposomal therapeutic antibody constructs.

Chiu GN, Edwards LA, Kapanen AI, Malinen MM, Dragowska WH, Warburton C, Chikh GG, Fang KY, Tan S, Sy J, Tucker C, Waterhouse DN, Klasa R, Bally MB. Chiu GN, et al. Among authors: waterhouse dn. Mol Cancer Ther. 2007 Mar;6(3):844-55. doi: 10.1158/1535-7163.MCT-06-0159. Epub 2007 Mar 5. Mol Cancer Ther. 2007. PMID: 17339368 Free article.

2

Combining doxorubicin and liposomal anti-HER-2/NEU antisense oligodeoxynucleotides to treat HER-2/NEU-expressing MDA-MB-435 breast tumor model.

Waterhouse DN, Gelmon KA, Masin D, Bally MB. Waterhouse DN, et al. J Exp Ther Oncol. 2003 Sep-Oct;3(5):261-71. doi: 10.1111/j.1533-869x.2003.01099.x. J Exp Ther Oncol. 2003. PMID: 14696623

3

Pharmacodynamic behavior of liposomal antisense oligonucleotides targeting Her-2/neu and vascular endothelial growth factor in an ascitic MDA435/LCC6 human breast cancer model.

Waterhouse DN, Dragowska WH, Gelmon KA, Mayer LD, Bally MB. Waterhouse DN, et al. Cancer Biol Ther. 2004 Feb;3(2):197-204. Epub 2004 Feb 1. Cancer Biol Ther. 2004. PMID: 14726684

4

Suppression of VEGF secretion and changes in glioblastoma multiforme microenvironment by inhibition of integrin-linked kinase (ILK).

Edwards LA, Woo J, Huxham LA, Verreault M, Dragowska WH, Chiu G, Rajput A, Kyle AH, Kalra J, Yapp D, Yan H, Minchinton AI, Huntsman D, Daynard T, Waterhouse DN, Thiessen B, Dedhar S, Bally MB. Edwards LA, et al. Among authors: waterhouse dn. Mol Cancer Ther. 2008 Jan;7(1):59-70. doi: 10.1158/1535-7163.MCT-07-0329. Mol Cancer Ther. 2008. PMID: 18202010

5

HER-2/neu overexpression increases the viable hypoxic cell population within solid tumors without causing changes in tumor vascularization.

Dragowska WH, Warburton C, Yapp DT, Minchinton AI, Hu Y, Waterhouse DN, Gelmon K, Skov K, Woo J, Masin D, Huxham LA, Kyle AH, Bally MB. Dragowska WH, et al. Among authors: waterhouse dn. Mol Cancer Res. 2004 Nov;2(11):606-19. Mol Cancer Res. 2004. PMID: 15561777

6

QLT0267, a small molecule inhibitor targeting integrin-linked kinase (ILK), and docetaxel can combine to produce synergistic interactions linked to enhanced cytotoxicity, reductions in P-AKT levels, altered F-actin architecture and improved treatment outcomes in an orthotopic breast cancer model.

Kalra J, Warburton C, Fang K, Edwards L, Daynard T, Waterhouse D, Dragowska W, Sutherland BW, Dedhar S, Gelmon K, Bally M. Kalra J, et al. Breast Cancer Res. 2009;11(3):R25. doi: 10.1186/bcr2252. Epub 2009 May 1. Breast Cancer Res. 2009. PMID: 19409087 Free PMC article.

7

The liposomal formulation of doxorubicin.

Abraham SA, Waterhouse DN, Mayer LD, Cullis PR, Madden TD, Bally MB. Abraham SA, et al. Among authors: waterhouse dn. Methods Enzymol. 2005;391:71-97. doi: 10.1016/S0076-6879(05)91004-5. Methods Enzymol. 2005. PMID: 15721375

8

Trastuzumab and liposomal Doxorubicin in the treatment of mcf-7 xenograft tumor-bearing mice: combination does not affect drug serum levels.

Waterhouse DN, Denyssevych T, Hudon N, Chia S, Gelmon KA, Bally MB. Waterhouse DN, et al. Pharm Res. 2005 Jun;22(6):915-22. doi: 10.1007/s11095-005-4586-z. Epub 2005 Jun 8. Pharm Res. 2005. PMID: 15948035

9

Topophore C: a liposomal nanoparticle formulation of topotecan for treatment of ovarian cancer.

Patankar NA, Waterhouse D, Strutt D, Anantha M, Bally MB. Patankar NA, et al. Invest New Drugs. 2013 Feb;31(1):46-58. doi: 10.1007/s10637-012-9832-8. Epub 2012 May 22. Invest New Drugs. 2013. PMID: 22615060

10

Development and assessment of conventional and targeted drug combinations for use in the treatment of aggressive breast cancers.

Waterhouse DN, Gelmon KA, Klasa R, Chi K, Huntsman D, Ramsay E, Wasan E, Edwards L, Tucker C, Zastre J, Wang YZ, Yapp D, Dragowska W, Dunn S, Dedhar S, Bally MB. Waterhouse DN, et al. Curr Cancer Drug Targets. 2006 Sep;6(6):455-89. doi: 10.2174/156800906778194586. Curr Cancer Drug Targets. 2006. PMID: 17017873 Review.

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