Schinazi RF - Search Results

1

Interaction of 2'-deoxyguanosine triphosphate analogue inhibitors of HIV reverse transcriptase with human mitochondrial DNA polymerase gamma.

Ray AS, Feng JY, Murakami E, Chu CK, Schinazi RF, Anderson KS. Ray AS, et al. Among authors: schinazi rf. Antivir Chem Chemother. 2007;18(1):25-33. doi: 10.1177/095632020701800103. Antivir Chem Chemother. 2007. PMID: 17354649 Free article.

2

Biochemical studies on the mechanism of human immunodeficiency virus type 1 reverse transcriptase resistance to 1-(beta-D-dioxolane)thymine triphosphate.

Lennerstrand J, Chu CK, Schinazi RF. Lennerstrand J, et al. Among authors: schinazi rf. Antimicrob Agents Chemother. 2007 Jun;51(6):2078-84. doi: 10.1128/AAC.00119-07. Epub 2007 Apr 2. Antimicrob Agents Chemother. 2007. PMID: 17403997 Free PMC article.

3

Pre-steady-state kinetic studies establish entecavir 5'-triphosphate as a substrate for HIV-1 reverse transcriptase.

Domaoal RA, McMahon M, Thio CL, Bailey CM, Tirado-Rives J, Obikhod A, Detorio M, Rapp KL, Siliciano RF, Schinazi RF, Anderson KS. Domaoal RA, et al. Among authors: schinazi rf. J Biol Chem. 2008 Feb 29;283(9):5452-9. doi: 10.1074/jbc.M707834200. Epub 2007 Oct 25. J Biol Chem. 2008. PMID: 17962184 Free PMC article.

4

Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase γ.

Sohl CD, Szymanski MR, Mislak AC, Shumate CK, Amiralaei S, Schinazi RF, Anderson KS, Yin YW. Sohl CD, et al. Among authors: schinazi rf. Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):8596-601. doi: 10.1073/pnas.1421733112. Epub 2015 Jun 29. Proc Natl Acad Sci U S A. 2015. PMID: 26124101 Free PMC article.

5

Structural insights into the recognition of nucleoside reverse transcriptase inhibitors by HIV-1 reverse transcriptase: First crystal structures with reverse transcriptase and the active triphosphate forms of lamivudine and emtricitabine.

Bertoletti N, Chan AH, Schinazi RF, Yin YW, Anderson KS. Bertoletti N, et al. Among authors: schinazi rf. Protein Sci. 2019 Sep;28(9):1664-1675. doi: 10.1002/pro.3681. Epub 2019 Aug 6. Protein Sci. 2019. PMID: 31301259 Free PMC article.

6

Insights into the molecular mechanism of inhibition and drug resistance for HIV-1 RT with carbovir triphosphate.

Ray AS, Yang Z, Shi J, Hobbs A, Schinazi RF, Chu CK, Anderson KS. Ray AS, et al. Among authors: schinazi rf. Biochemistry. 2002 Apr 23;41(16):5150-62. doi: 10.1021/bi0121858. Biochemistry. 2002. PMID: 11955063

7

Interactions of enantiomers of 2',3'-didehydro-2',3'-dideoxy-fluorocytidine with wild type and M184V mutant HIV-1 reverse transcriptase.

Ray AS, Murakami E, Peterson CN, Shi J, Schinazi RF, Anderson KS. Ray AS, et al. Among authors: schinazi rf. Antiviral Res. 2002 Dec;56(3):189-205. doi: 10.1016/s0166-3542(02)00102-x. Antiviral Res. 2002. PMID: 12406504

8

Probing the molecular mechanisms of AZT drug resistance mediated by HIV-1 reverse transcriptase using a transient kinetic analysis.

Ray AS, Murakami E, Basavapathruni A, Vaccaro JA, Ulrich D, Chu CK, Schinazi RF, Anderson KS. Ray AS, et al. Among authors: schinazi rf. Biochemistry. 2003 Jul 29;42(29):8831-41. doi: 10.1021/bi034435l. Biochemistry. 2003. PMID: 12873144

9

Probing the mechanistic consequences of 5-fluorine substitution on cytidine nucleotide analogue incorporation by HIV-1 reverse transcriptase.

Ray AS, Schinazi RF, Murakami E, Basavapathruni A, Shi J, Zorca SM, Chu CK, Anderson KS. Ray AS, et al. Among authors: schinazi rf. Antivir Chem Chemother. 2003 May;14(3):115-25. doi: 10.1177/095632020301400301. Antivir Chem Chemother. 2003. PMID: 14521328 Free article. Review.

10

Investigating the effects of stereochemistry on incorporation and removal of 5-fluorocytidine analogs by mitochondrial DNA polymerase gamma: comparison of D- and L-D4FC-TP.

Murakami E, Ray AS, Schinazi RF, Anderson KS. Murakami E, et al. Among authors: schinazi rf. Antiviral Res. 2004 Apr;62(1):57-64. doi: 10.1016/j.antiviral.2003.12.001. Antiviral Res. 2004. PMID: 15026203

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