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SIV-specific CD8+ T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection.
Petrovas C, Price DA, Mattapallil J, Ambrozak DR, Geldmacher C, Cecchinato V, Vaccari M, Tryniszewska E, Gostick E, Roederer M, Douek DC, Morgan SH, Davis SJ, Franchini G, Koup RA. Petrovas C, et al. Among authors: geldmacher c. Blood. 2007 Aug 1;110(3):928-36. doi: 10.1182/blood-2007-01-069112. Epub 2007 Apr 17. Blood. 2007. PMID: 17440051 Free PMC article.
Early risk assessment in paediatric and adult household contacts of confirmed tuberculosis cases by novel diagnostic tests (ERASE-TB): protocol for a prospective, non-interventional, longitudinal, multicountry cohort study.
Marambire ET, Banze D, Mfinanga A, Mutsvangwa J, Mbunda TD, Ntinginya NE, Celso K, Kallenius G, Calderwood CJ, Geldmacher C, Held K, Appalarowthu T, Rieß F, Panzner U, Heinrich N, Kranzer K; ERASE-TB Consortium. Marambire ET, et al. Among authors: geldmacher c. BMJ Open. 2022 Jul 19;12(7):e060985. doi: 10.1136/bmjopen-2022-060985. BMJ Open. 2022. PMID: 36427173 Free PMC article.
CD8 T-cell recognition of multiple epitopes within specific Gag regions is associated with maintenance of a low steady-state viremia in human immunodeficiency virus type 1-seropositive patients.
Geldmacher C, Currier JR, Herrmann E, Haule A, Kuta E, McCutchan F, Njovu L, Geis S, Hoffmann O, Maboko L, Williamson C, Birx D, Meyerhans A, Cox J, Hoelscher M. Geldmacher C, et al. J Virol. 2007 Mar;81(5):2440-8. doi: 10.1128/JVI.01847-06. Epub 2006 Dec 20. J Virol. 2007. PMID: 17182686 Free PMC article.
Minor viral and host genetic polymorphisms can dramatically impact the biologic outcome of an epitope-specific CD8 T-cell response.
Geldmacher C, Metzler IS, Tovanabutra S, Asher TE, Gostick E, Ambrozak DR, Petrovas C, Schuetz A, Ngwenyama N, Kijak G, Maboko L, Hoelscher M, McCutchan F, Price DA, Douek DC, Koup RA. Geldmacher C, et al. Blood. 2009 Aug 20;114(8):1553-62. doi: 10.1182/blood-2009-02-206193. Epub 2009 Jun 19. Blood. 2009. PMID: 19542300 Free PMC article.
Differential association of programmed death-1 and CD57 with ex vivo survival of CD8+ T cells in HIV infection.
Petrovas C, Chaon B, Ambrozak DR, Price DA, Melenhorst JJ, Hill BJ, Geldmacher C, Casazza JP, Chattopadhyay PK, Roederer M, Douek DC, Mueller YM, Jacobson JM, Kulkarni V, Felber BK, Pavlakis GN, Katsikis PD, Koup RA. Petrovas C, et al. Among authors: geldmacher c. J Immunol. 2009 Jul 15;183(2):1120-32. doi: 10.4049/jimmunol.0900182. Epub 2009 Jun 29. J Immunol. 2009. PMID: 19564339 Free PMC article.
Preferential infection and depletion of Mycobacterium tuberculosis-specific CD4 T cells after HIV-1 infection.
Geldmacher C, Ngwenyama N, Schuetz A, Petrovas C, Reither K, Heeregrave EJ, Casazza JP, Ambrozak DR, Louder M, Ampofo W, Pollakis G, Hill B, Sanga E, Saathoff E, Maboko L, Roederer M, Paxton WA, Hoelscher M, Koup RA. Geldmacher C, et al. J Exp Med. 2010 Dec 20;207(13):2869-81. doi: 10.1084/jem.20100090. Epub 2010 Nov 29. J Exp Med. 2010. PMID: 21115690 Free PMC article.
95 results