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SIV-specific CD8+ T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection.
Petrovas C, Price DA, Mattapallil J, Ambrozak DR, Geldmacher C, Cecchinato V, Vaccari M, Tryniszewska E, Gostick E, Roederer M, Douek DC, Morgan SH, Davis SJ, Franchini G, Koup RA. Petrovas C, et al. Among authors: koup ra. Blood. 2007 Aug 1;110(3):928-36. doi: 10.1182/blood-2007-01-069112. Epub 2007 Apr 17. Blood. 2007. PMID: 17440051 Free PMC article.
Evidence for thymic function in the elderly.
Douek DC, Koup RA. Douek DC, et al. Among authors: koup ra. Vaccine. 2000 Feb 25;18(16):1638-41. doi: 10.1016/s0264-410x(99)00499-5. Vaccine. 2000. PMID: 10689141 Review.
Identification of a human recent thymic emigrant phenotype.
McFarland RD, Douek DC, Koup RA, Picker LJ. McFarland RD, et al. Among authors: koup ra. Proc Natl Acad Sci U S A. 2000 Apr 11;97(8):4215-20. doi: 10.1073/pnas.070061597. Proc Natl Acad Sci U S A. 2000. PMID: 10737767 Free PMC article.
Quantification of thymic function by measuring T cell receptor excision circles within peripheral blood and lymphoid tissues in monkeys.
Sodora DL, Douek DC, Silvestri G, Montgomery L, Rosenzweig M, Igarashi T, Bernacky B, Johnson RP, Feinberg MB, Martin MA, Koup RA. Sodora DL, et al. Among authors: koup ra. Eur J Immunol. 2000 Apr;30(4):1145-53. doi: 10.1002/(SICI)1521-4141(200004)30:4<1145::AID-IMMU1145>3.0.CO;2-7. Eur J Immunol. 2000. PMID: 10760804 Free article.
Evidence for increased T cell turnover and decreased thymic output in HIV infection.
Douek DC, Betts MR, Hill BJ, Little SJ, Lempicki R, Metcalf JA, Casazza J, Yoder C, Adelsberger JW, Stevens RA, Baseler MW, Keiser P, Richman DD, Davey RT, Koup RA. Douek DC, et al. Among authors: koup ra. J Immunol. 2001 Dec 1;167(11):6663-8. doi: 10.4049/jimmunol.167.11.6663. J Immunol. 2001. PMID: 11714838
432 results