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The VAD-DCEP sequence is an effective pre-transplant therapy in untreated multiple myeloma.
Corso A, Barbarano L, Zappasodi P, Cairoli R, Alessandrino EP, Mangiacavalli S, Ferrari D, Fava S, Fiumanò M, Frigerio G, Isa L, Luraschi A, Klersy C, De Paoli A, Vergani C, Banfi L, Perego D, Ucci G, Pinotti G, Savarè M, Uziel L, Vismara A, Morra E, Lazzarino M. Corso A, et al. Among authors: lazzarino m. Haematologica. 2004 Sep;89(9):1124-7. Haematologica. 2004. PMID: 15377474 Clinical Trial.
Bortezomib plus dexamethasone can improve stem cell collection and overcome the need for additional chemotherapy before autologous transplant in patients with myeloma.
Corso A, Barbarano L, Mangiacavalli S, Spriano M, Alessandrino EP, Cafro AM, Pascutto C, Varettoni M, Bernasconi P, Grillo G, Carella AM, Montalbetti L, Lazzarino M, Morra E. Corso A, et al. Among authors: lazzarino m. Leuk Lymphoma. 2010 Feb;51(2):236-42. doi: 10.3109/10428190903452826. Leuk Lymphoma. 2010. PMID: 20001242 Clinical Trial.
A combination of dexamethasone, cyclophosphamide, etoposide, and cisplatin is less toxic and more effective than high-dose cyclophosphamide for peripheral stem cell mobilization in multiple myeloma.
Corso A, Arcaini L, Caberlon S, Zappasodi P, Mangiacavalli S, Lorenzi A, Rusconi C, Troletti D, Maiocchi MA, Pascutto C, Morra E, Lazzarino M. Corso A, et al. Among authors: lazzarino m. Haematologica. 2002 Oct;87(10):1041-5. Haematologica. 2002. PMID: 12368158
DCEP (dexamethasone, cyclophosphamide, etoposide, and cisplatin) is an effective regimen for peripheral blood stem cell collection in multiple myeloma.
Lazzarino M, Corso A, Barbarano L, Alessandrino EP, Cairoli R, Pinotti G, Ucci G, Uziel L, Rodeghiero F, Fava S, Ferrari D, Fiumanò M, Frigerio G, Isa L, Luraschi A, Montanara S, Morandi S, Perego D, Santagostino A, Savarè M, Vismara A, Morra E. Lazzarino M, et al. Bone Marrow Transplant. 2001 Nov;28(9):835-9. doi: 10.1038/sj.bmt.1703240. Bone Marrow Transplant. 2001. PMID: 11781643
345 results