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Xenograft models for the preclinical evaluation of new therapies in acute leukemia.
Leuk Lymphoma. 2007 Apr;48(4):659-68. doi: 10.1080/10428190601113584.
Leuk Lymphoma. 2007.
PMID: 17454623
Review.
Divergent mechanisms of glucocorticoid resistance in experimental models of pediatric acute lymphoblastic leukemia.
Bachmann PS, Gorman R, Papa RA, Bardell JE, Ford J, Kees UR, Marshall GM, Lock RB.
Bachmann PS, et al.
Cancer Res. 2007 May 1;67(9):4482-90. doi: 10.1158/0008-5472.CAN-06-4244.
Cancer Res. 2007.
PMID: 17483364
Item in Clipboard
In vivo models of childhood leukemia for preclinical drug testing.
Bachmann PS, Lock RB.
Bachmann PS, et al.
Curr Drug Targets. 2007 Jun;8(6):773-83. doi: 10.2174/138945007780830809.
Curr Drug Targets. 2007.
PMID: 17584033
Review.
Item in Clipboard
Epigenetic silencing of BIM in glucocorticoid poor-responsive pediatric acute lymphoblastic leukemia, and its reversal by histone deacetylase inhibition.
Bachmann PS, Piazza RG, Janes ME, Wong NC, Davies C, Mogavero A, Bhadri VA, Szymanska B, Geninson G, Magistroni V, Cazzaniga G, Biondi A, Miranda-Saavedra D, Göttgens B, Saffery R, Craig JM, Marshall GM, Gambacorti-Passerini C, Pimanda JE, Lock RB.
Bachmann PS, et al.
Blood. 2010 Oct 21;116(16):3013-22. doi: 10.1182/blood-2010-05-284968. Epub 2010 Jul 20.
Blood. 2010.
PMID: 20647567
Free article.
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p53-independent epigenetic repression of the p21(WAF1) gene in T-cell acute lymphoblastic leukemia.
Davies C, Hogarth LA, Dietrich PA, Bachmann PS, Mackenzie KL, Hall AG, Lock RB.
Davies C, et al. Among authors: bachmann ps.
J Biol Chem. 2011 Oct 28;286(43):37639-50. doi: 10.1074/jbc.M111.272336. Epub 2011 Sep 7.
J Biol Chem. 2011.
PMID: 21903579
Free PMC article.
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Dexamethasone resistance in B-cell precursor childhood acute lymphoblastic leukemia occurs downstream of ligand-induced nuclear translocation of the glucocorticoid receptor.
Bachmann PS, Gorman R, Mackenzie KL, Lutze-Mann L, Lock RB.
Bachmann PS, et al.
Blood. 2005 Mar 15;105(6):2519-26. doi: 10.1182/blood-2004-05-2023. Epub 2004 Nov 30.
Blood. 2005.
PMID: 15572593
Free article.
Item in Clipboard
Epigenetic silencing of the proapoptotic gene BIM in anaplastic large cell lymphoma through an MeCP2/SIN3a deacetylating complex.
Piazza R, Magistroni V, Mogavero A, Andreoni F, Ambrogio C, Chiarle R, Mologni L, Bachmann PS, Lock RB, Collini P, Pelosi G, Gambacorti-Passerini C.
Piazza R, et al. Among authors: bachmann ps.
Neoplasia. 2013 May;15(5):511-22. doi: 10.1593/neo.121784.
Neoplasia. 2013.
PMID: 23633923
Free PMC article.
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