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Page 1
Novel role of triazenes in haematological malignancies: pilot study of Temozolomide, Lomeguatrib and IL-2 in the chemo-immunotherapy of acute leukaemia.
Caporaso P, Turriziani M, Venditti A, Marchesi F, Buccisano F, Tirindelli MC, Alvino E, Garbin A, Tortorelli G, Toppo L, Bonmassar E, D'Atri S, Amadori S. Caporaso P, et al. Among authors: bonmassar e. DNA Repair (Amst). 2007 Aug 1;6(8):1179-86. doi: 10.1016/j.dnarep.2007.03.016. Epub 2007 May 17. DNA Repair (Amst). 2007. PMID: 17500047
O6-(4-bromothenyl)guanine (PaTrin-2), a novel inhibitor of O6-alkylguanine DNA alkyl-transferase, increases the inhibitory activity of temozolomide against human acute leukaemia cells in vitro.
Turriziani M, Caporaso P, Bonmassar L, Buccisano F, Amadori S, Venditti A, Cantonetti M, D'Atri S, Bonmassar E. Turriziani M, et al. Among authors: bonmassar e, bonmassar l. Pharmacol Res. 2006 Apr;53(4):317-23. doi: 10.1016/j.phrs.2005.12.001. Epub 2006 Jan 10. Pharmacol Res. 2006. PMID: 16412662
A single cycle of treatment with temozolomide, alone or combined with O(6)-benzylguanine, induces strong chemoresistance in melanoma cell clones in vitro: role of O(6)-methylguanine-DNA methyltransferase and the mismatch repair system.
Alvino E, Castiglia D, Caporali S, Pepponi R, Caporaso P, Lacal PM, Marra G, Fischer F, Zambruno G, Bonmassar E, Jiricny J, D'Atri S. Alvino E, et al. Among authors: bonmassar e. Int J Oncol. 2006 Oct;29(4):785-97. Int J Oncol. 2006. PMID: 16964376
The cyclin-dependent kinase inhibitor PHA-848125 suppresses the in vitro growth of human melanomas sensitive or resistant to temozolomide, and shows synergistic effects in combination with this triazene compound.
Caporali S, Alvino E, Starace G, Ciomei M, Brasca MG, Levati L, Garbin A, Castiglia D, Covaciu C, Bonmassar E, D'Atri S. Caporali S, et al. Among authors: bonmassar e. Pharmacol Res. 2010 May;61(5):437-48. doi: 10.1016/j.phrs.2009.12.009. Epub 2009 Dec 21. Pharmacol Res. 2010. PMID: 20026273
Focus on Fotemustine.
De Rossi A, Rossi L, Laudisi A, Sini V, Toppo L, Marchesi F, Tortorelli G, Leti M, Turriziani M, Aquino A, Bonmassar E, De Vecchis L, Torino F. De Rossi A, et al. Among authors: bonmassar e. J Exp Clin Cancer Res. 2006 Dec;25(4):461-8. J Exp Clin Cancer Res. 2006. PMID: 17310834 Review.
258 results