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Model-based drug development.
Lalonde RL, Kowalski KG, Hutmacher MM, Ewy W, Nichols DJ, Milligan PA, Corrigan BW, Lockwood PA, Marshall SA, Benincosa LJ, Tensfeldt TG, Parivar K, Amantea M, Glue P, Koide H, Miller R. Lalonde RL, et al. Among authors: miller r. Clin Pharmacol Ther. 2007 Jul;82(1):21-32. doi: 10.1038/sj.clpt.6100235. Epub 2007 May 23. Clin Pharmacol Ther. 2007. PMID: 17522597 Review.
How modeling and simulation have enhanced decision making in new drug development.
Miller R, Ewy W, Corrigan BW, Ouellet D, Hermann D, Kowalski KG, Lockwood P, Koup JR, Donevan S, El-Kattan A, Li CS, Werth JL, Feltner DE, Lalonde RL. Miller R, et al. J Pharmacokinet Pharmacodyn. 2005 Apr;32(2):185-97. doi: 10.1007/s10928-005-0074-7. Epub 2005 Nov 7. J Pharmacokinet Pharmacodyn. 2005. PMID: 16283534 Review.
A two-part mixture model for longitudinal adverse event severity data.
Kowalski KG, McFadyen L, Hutmacher MM, Frame B, Miller R. Kowalski KG, et al. Among authors: miller r. J Pharmacokinet Pharmacodyn. 2003 Oct;30(5):315-36. doi: 10.1023/b:jopa.0000008157.26321.3c. J Pharmacokinet Pharmacodyn. 2003. PMID: 14977163
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