Dole WP - Search Results

1

Thiophene-anthranilamides as highly potent and orally available factor Xa inhibitors.

Ye B, Arnaiz DO, Chou YL, Griedel BD, Karanjawala R, Lee W, Morrissey MM, Sacchi KL, Sakata ST, Shaw KJ, Wu SC, Zhao Z, Adler M, Cheeseman S, Dole WP, Ewing J, Fitch R, Lentz D, Liang A, Light D, Morser J, Post J, Rumennik G, Subramanyam B, Sullivan ME, Vergona R, Walters J, Wang YX, White KA, Whitlow M, Kochanny MJ. Ye B, et al. Among authors: dole wp. J Med Chem. 2007 Jun 28;50(13):2967-80. doi: 10.1021/jm070125f. Epub 2007 May 31. J Med Chem. 2007. PMID: 17536795

2

A novel P2Y(12) adenosine diphosphate receptor antagonist that inhibits platelet aggregation and thrombus formation in rat and dog models.

Wang YX, Vincelette J, da Cunha V, Martin-McNulty B, Mallari C, Fitch RM, Alexander S, Islam I, Buckman BO, Yuan S, Post JM, Subramanyam B, Vergona R, Sullivan ME, Dole WP, Morser J, Bryant J. Wang YX, et al. Among authors: dole wp. Thromb Haemost. 2007 May;97(5):847-55. Thromb Haemost. 2007. PMID: 17479197

3

Characterization of a small molecule PAI-1 inhibitor, ZK4044.

Liang A, Wu F, Tran K, Jones SW, Deng G, Ye B, Zhao Z, Snider RM, Dole WP, Morser J, Wu Q. Liang A, et al. Among authors: dole wp. Thromb Res. 2005;115(4):341-50. doi: 10.1016/j.thromres.2004.09.021. Epub 2004 Nov 13. Thromb Res. 2005. PMID: 15668194

4

Novel P2Y12 adenosine diphosphate receptor antagonists for inhibition of platelet aggregation (II): pharmacodynamic and pharmacokinetic characterization.

Post JM, Alexander S, Wang YX, Vincelette J, Vergona R, Kent L, Bryant J, Sullivan ME, Dole WP, Morser J, Subramanyam B. Post JM, et al. Among authors: dole wp. Thromb Res. 2008;122(4):533-40. doi: 10.1016/j.thromres.2008.04.009. Epub 2008 Jun 9. Thromb Res. 2008. PMID: 18539312

5

P-selectin-targeting of the fibrin selective thrombolytic Desmodus rotundus salivary plasminogen activator alpha1.

Dong N, Da Cunha V, Citkowicz A, Wu F, Vincelette J, Larsen B, Wang YX, Ruan C, Dole WP, Morser J, Wu Q, Pan J. Dong N, et al. Among authors: dole wp. Thromb Haemost. 2004 Nov;92(5):956-65. doi: 10.1160/TH04-03-0177. Thromb Haemost. 2004. PMID: 15543321

6

Inhibition of rho-kinase by hydroxyfasudil prevents vasopressin-induced myocardial ischemia in Donryu rats by attenuating coronary vasoconstriction.

Vincelette J, Pagila R, Kawai K, Ishii M, Horimizu Y, Vergona R, Sullivan ME, Morser J, Dole WP, Wang YX. Vincelette J, et al. Among authors: dole wp. Pharmacology. 2005 Nov;75(3):145-51. doi: 10.1159/000088280. Epub 2005 Sep 12. Pharmacology. 2005. PMID: 16158013

7

A novel inhibitor of activated thrombin activatable fibrinolysis inhibitor (TAFIa) - part II: enhancement of both exogenous and endogenous fibrinolysis in animal models of thrombosis.

Wang YX, da Cunha V, Vincelette J, Zhao L, Nagashima M, Kawai K, Yuan S, Emayan K, Islam I, Hosoya J, Sullivan ME, Dole WP, Morser J, Buckman BO, Vergona R. Wang YX, et al. Among authors: dole wp. Thromb Haemost. 2007 Jan;97(1):54-61. Thromb Haemost. 2007. PMID: 17200771

8

Increased nitric oxide accounts for decreased basal vascular tone and responsiveness in the resistance vessels of high-cholesterol-fed rabbits.

Fitch R, Da Cunha V, Kauser K, Dole W, Parkinson J, Vergona R, Sullivan ME, Wang YX. Fitch R, et al. Pharmacology. 2001;63(4):220-7. doi: 10.1159/000056137. Pharmacology. 2001. PMID: 11729360

9

Angiotensin II increases urokinase-type plasminogen activator expression and induces aneurysm in the abdominal aorta of apolipoprotein E-deficient mice.

Wang YX, Martin-McNulty B, Freay AD, Sukovich DA, Halks-Miller M, Li WW, Vergona R, Sullivan ME, Morser J, Dole WP, Deng GG. Wang YX, et al. Among authors: dole wp. Am J Pathol. 2001 Oct;159(4):1455-64. doi: 10.1016/S0002-9440(10)62532-1. Am J Pathol. 2001. PMID: 11583973 Free PMC article.

10

Overexpression of PAI-1 prevents the development of abdominal aortic aneurysm in mice.

Qian HS, Gu JM, Liu P, Kauser K, Halks-Miller M, Vergona R, Sullivan ME, Dole WP, Deng GG. Qian HS, et al. Among authors: dole wp. Gene Ther. 2008 Feb;15(3):224-32. doi: 10.1038/sj.gt.3303069. Epub 2007 Nov 22. Gene Ther. 2008. PMID: 18033310

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