Morser J - Search Results

1

Thiophene-anthranilamides as highly potent and orally available factor Xa inhibitors.

Ye B, Arnaiz DO, Chou YL, Griedel BD, Karanjawala R, Lee W, Morrissey MM, Sacchi KL, Sakata ST, Shaw KJ, Wu SC, Zhao Z, Adler M, Cheeseman S, Dole WP, Ewing J, Fitch R, Lentz D, Liang A, Light D, Morser J, Post J, Rumennik G, Subramanyam B, Sullivan ME, Vergona R, Walters J, Wang YX, White KA, Whitlow M, Kochanny MJ. Ye B, et al. Among authors: morser j. J Med Chem. 2007 Jun 28;50(13):2967-80. doi: 10.1021/jm070125f. Epub 2007 May 31. J Med Chem. 2007. PMID: 17536795

2

Discovery and characterization of a potent and selective non-amidine inhibitor of human factor Xa.

Liang AM, Light DR, Kochanny M, Rumennik G, Trinh L, Lentz D, Post J, Morser J, Snider M. Liang AM, et al. Among authors: morser j. Biochem Pharmacol. 2003 May 1;65(9):1407-18. doi: 10.1016/s0006-2952(03)00084-4. Biochem Pharmacol. 2003. PMID: 12732352

3

3-Mercaptopropionic acids as efficacious inhibitors of activated thrombin activatable fibrinolysis inhibitor (TAFIa).

Islam I, Bryant J, May K, Mohan R, Yuan S, Kent L, Morser J, Zhao L, Vergona R, White K, Adler M, Whitlow M, Buckman BO. Islam I, et al. Among authors: morser j. Bioorg Med Chem Lett. 2007 Mar 1;17(5):1349-54. doi: 10.1016/j.bmcl.2006.11.078. Epub 2006 Dec 3. Bioorg Med Chem Lett. 2007. PMID: 17189688

4

A novel P2Y(12) adenosine diphosphate receptor antagonist that inhibits platelet aggregation and thrombus formation in rat and dog models.

Wang YX, Vincelette J, da Cunha V, Martin-McNulty B, Mallari C, Fitch RM, Alexander S, Islam I, Buckman BO, Yuan S, Post JM, Subramanyam B, Vergona R, Sullivan ME, Dole WP, Morser J, Bryant J. Wang YX, et al. Among authors: morser j. Thromb Haemost. 2007 May;97(5):847-55. Thromb Haemost. 2007. PMID: 17479197

5

Discovery of selective urokinase plasminogen activator (uPA) inhibitors as a potential treatment for multiple sclerosis.

Islam I, Yuan S, West CW, Adler M, Bothe U, Bryant J, Chang Z, Chu K, Emayan K, Gualtieri G, Ho E, Light D, Mallari C, Morser J, Phillips G, Schaefer C, Sukovich D, Whitlow M, Chen D, Buckman BO. Islam I, et al. Among authors: morser j. Bioorg Med Chem Lett. 2018 Nov 1;28(20):3372-3375. doi: 10.1016/j.bmcl.2018.09.001. Epub 2018 Sep 5. Bioorg Med Chem Lett. 2018. PMID: 30201291

6

Characterization of a small molecule PAI-1 inhibitor, ZK4044.

Liang A, Wu F, Tran K, Jones SW, Deng G, Ye B, Zhao Z, Snider RM, Dole WP, Morser J, Wu Q. Liang A, et al. Among authors: morser j. Thromb Res. 2005;115(4):341-50. doi: 10.1016/j.thromres.2004.09.021. Epub 2004 Nov 13. Thromb Res. 2005. PMID: 15668194

7

Novel P2Y12 adenosine diphosphate receptor antagonists for inhibition of platelet aggregation (I): in vitro effects on platelets.

Bryant J, Post JM, Alexander S, Wang YX, Kent L, Schirm S, Tseng JL, Subramanyam B, Buckman B, Islam I, Yuan S, Sullivan ME, Snider M, Morser J. Bryant J, et al. Among authors: morser j. Thromb Res. 2008;122(4):523-32. doi: 10.1016/j.thromres.2008.03.026. Epub 2008 May 20. Thromb Res. 2008. PMID: 18495218

8

Novel P2Y12 adenosine diphosphate receptor antagonists for inhibition of platelet aggregation (II): pharmacodynamic and pharmacokinetic characterization.

Post JM, Alexander S, Wang YX, Vincelette J, Vergona R, Kent L, Bryant J, Sullivan ME, Dole WP, Morser J, Subramanyam B. Post JM, et al. Among authors: morser j. Thromb Res. 2008;122(4):533-40. doi: 10.1016/j.thromres.2008.04.009. Epub 2008 Jun 9. Thromb Res. 2008. PMID: 18539312

9

A novel inhibitor of activated thrombin activatable fibrinolysis inhibitor (TAFIa) - part II: enhancement of both exogenous and endogenous fibrinolysis in animal models of thrombosis.

Wang YX, da Cunha V, Vincelette J, Zhao L, Nagashima M, Kawai K, Yuan S, Emayan K, Islam I, Hosoya J, Sullivan ME, Dole WP, Morser J, Buckman BO, Vergona R. Wang YX, et al. Among authors: morser j. Thromb Haemost. 2007 Jan;97(1):54-61. Thromb Haemost. 2007. PMID: 17200771

10

The structure of a 19-residue fragment from the C-loop of the fourth epidermal growth factor-like domain of thrombomodulin.

Adler M, Seto MH, Nitecki DE, Lin JH, Light DR, Morser J. Adler M, et al. Among authors: morser j. J Biol Chem. 1995 Oct 6;270(40):23366-72. doi: 10.1074/jbc.270.40.23366. J Biol Chem. 1995. PMID: 7559494 Free article.

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