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349 results

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Randomized trial of the combination of lomeguatrib and temozolomide compared with temozolomide alone in chemotherapy naive patients with metastatic cutaneous melanoma.
Ranson M, Hersey P, Thompson D, Beith J, McArthur GA, Haydon A, Davis ID, Kefford RF, Mortimer P, Harris PA, Baka S, Seebaran A, Sabharwal A, Watson AJ, Margison GP, Middleton MR. Ranson M, et al. J Clin Oncol. 2007 Jun 20;25(18):2540-5. doi: 10.1200/JCO.2007.10.8217. J Clin Oncol. 2007. PMID: 17577032 Clinical Trial.
Lomeguatrib, a potent inhibitor of O6-alkylguanine-DNA-alkyltransferase: phase I safety, pharmacodynamic, and pharmacokinetic trial and evaluation in combination with temozolomide in patients with advanced solid tumors.
Ranson M, Middleton MR, Bridgewater J, Lee SM, Dawson M, Jowle D, Halbert G, Waller S, McGrath H, Gumbrell L, McElhinney RS, Donnelly D, McMurry TB, Margison GP. Ranson M, et al. Clin Cancer Res. 2006 Mar 1;12(5):1577-84. doi: 10.1158/1078-0432.CCR-05-2198. Clin Cancer Res. 2006. PMID: 16533784 Clinical Trial.
A phase II trial of lomeguatrib and temozolomide in metastatic colorectal cancer.
Khan OA, Ranson M, Michael M, Olver I, Levitt NC, Mortimer P, Watson AJ, Margison GP, Midgley R, Middleton MR. Khan OA, et al. Among authors: ranson m. Br J Cancer. 2008 May 20;98(10):1614-8. doi: 10.1038/sj.bjc.6604366. Epub 2008 May 13. Br J Cancer. 2008. PMID: 18475294 Free PMC article. Clinical Trial.
O(6)-methylguanine-DNA methyltransferase depletion and DNA damage in patients with melanoma treated with temozolomide alone or with lomeguatrib.
Watson AJ, Middleton MR, McGown G, Thorncroft M, Ranson M, Hersey P, McArthur G, Davis ID, Thomson D, Beith J, Haydon A, Kefford R, Lorigan P, Mortimer P, Sabharwal A, Hayward O, Margison GP. Watson AJ, et al. Among authors: ranson m. Br J Cancer. 2009 Apr 21;100(8):1250-6. doi: 10.1038/sj.bjc.6605015. Br J Cancer. 2009. PMID: 19367283 Free PMC article. Clinical Trial.
Phase III trial of gemcitabine and carboplatin versus mitomycin, ifosfamide, and cisplatin or mitomycin, vinblastine, and cisplatin in patients with advanced nonsmall cell lung carcinoma.
Danson S, Middleton MR, O'Byrne KJ, Clemons M, Ranson M, Hassan J, Anderson H, Burt PA, Fairve-Finn C, Stout R, Dowd I, Ashcroft L, Beresford C, Thatcher N. Danson S, et al. Among authors: ranson m. Cancer. 2003 Aug 1;98(3):542-53. doi: 10.1002/cncr.11535. Cancer. 2003. PMID: 12879472 Free article. Clinical Trial.
349 results