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The pannexin 1 channel activates the inflammasome in neurons and astrocytes.
Silverman WR, de Rivero Vaccari JP, Locovei S, Qiu F, Carlsson SK, Scemes E, Keane RW, Dahl G. Silverman WR, et al. Among authors: keane rw. J Biol Chem. 2009 Jul 3;284(27):18143-51. doi: 10.1074/jbc.M109.004804. Epub 2009 May 5. J Biol Chem. 2009. PMID: 19416975 Free PMC article.
Pannexin: from discovery to bedside in 11±4 years?
Dahl G, Keane RW. Dahl G, et al. Among authors: keane rw. Brain Res. 2012 Dec 3;1487:150-9. doi: 10.1016/j.brainres.2012.04.058. Epub 2012 Jul 4. Brain Res. 2012. PMID: 22771709 Free PMC article. Review.
Pyroptotic neuronal cell death mediated by the AIM2 inflammasome.
Adamczak SE, de Rivero Vaccari JP, Dale G, Brand FJ 3rd, Nonner D, Bullock MR, Dahl GP, Dietrich WD, Keane RW. Adamczak SE, et al. Among authors: keane rw. J Cereb Blood Flow Metab. 2014 Apr;34(4):621-9. doi: 10.1038/jcbfm.2013.236. Epub 2014 Jan 8. J Cereb Blood Flow Metab. 2014. PMID: 24398937 Free PMC article.
Human astrocytes express a novel NLRP2 inflammasome.
Minkiewicz J, de Rivero Vaccari JP, Keane RW. Minkiewicz J, et al. Among authors: keane rw. Glia. 2013 Jul;61(7):1113-21. doi: 10.1002/glia.22499. Epub 2013 Apr 26. Glia. 2013. PMID: 23625868
105 results