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The clinical grade maturation cocktail monophosphoryl lipid A plus IFNgamma generates monocyte-derived dendritic cells with the capacity to migrate and induce Th1 polarization.
Vaccine. 2007 Oct 10;25(41):7145-52. doi: 10.1016/j.vaccine.2007.07.031. Epub 2007 Aug 6.
Vaccine. 2007.
PMID: 17719152
Generation of dendritic cells for immunotherapy is minimally impaired by granulocytes in the monocyte preparation.
ten Brinke A, Karsten ML, Dieker MC, Zwaginga JJ, Vrielink H, Marieke van Ham S.
ten Brinke A, et al. Among authors: karsten ml.
Immunobiology. 2006;211(6-8):633-40. doi: 10.1016/j.imbio.2006.05.012. Epub 2006 Jul 5.
Immunobiology. 2006.
PMID: 16920502
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4-Hydroxy-oxyphenbutazone is a potent inhibitor of cytokine production.
Ten Brinke A, Dekkers DW, Notten SM, Karsten ML, de Groot ER, Aarden LA.
Ten Brinke A, et al. Among authors: karsten ml.
Eur Cytokine Netw. 2005 Jun;16(2):144-51.
Eur Cytokine Netw. 2005.
PMID: 15941686
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