Reed SI - Search Results

1

FBXW7/hCDC4 is a general tumor suppressor in human cancer.

Akhoondi S, Sun D, von der Lehr N, Apostolidou S, Klotz K, Maljukova A, Cepeda D, Fiegl H, Dafou D, Marth C, Mueller-Holzner E, Corcoran M, Dagnell M, Nejad SZ, Nayer BN, Zali MR, Hansson J, Egyhazi S, Petersson F, Sangfelt P, Nordgren H, Grander D, Reed SI, Widschwendter M, Sangfelt O, Spruck C. Akhoondi S, et al. Among authors: reed si. Cancer Res. 2007 Oct 1;67(19):9006-12. doi: 10.1158/0008-5472.CAN-07-1320. Cancer Res. 2007. PMID: 17909001

2

hCDC4 gene mutations in endometrial cancer.

Spruck CH, Strohmaier H, Sangfelt O, Müller HM, Hubalek M, Müller-Holzner E, Marth C, Widschwendter M, Reed SI. Spruck CH, et al. Among authors: reed si. Cancer Res. 2002 Aug 15;62(16):4535-9. Cancer Res. 2002. PMID: 12183400

3

Mutation of hCDC4 leads to cell cycle deregulation of cyclin E in cancer.

Ekholm-Reed S, Spruck CH, Sangfelt O, van Drogen F, Mueller-Holzner E, Widschwendter M, Zetterberg A, Reed SI. Ekholm-Reed S, et al. Among authors: reed si. Cancer Res. 2004 Feb 1;64(3):795-800. doi: 10.1158/0008-5472.can-03-3417. Cancer Res. 2004. PMID: 14871801

4

Both SCF(Cdc4alpha) and SCF(Cdc4gamma) are required for cyclin E turnover in cell lines that do not overexpress cyclin E.

Sangfelt O, Cepeda D, Malyukova A, van Drogen F, Reed SI. Sangfelt O, et al. Among authors: reed si. Cell Cycle. 2008 Apr 15;7(8):1075-82. doi: 10.4161/cc.7.8.5648. Epub 2008 Jan 17. Cell Cycle. 2008. PMID: 18414042

5

Fbw7α and Fbw7γ collaborate to shuttle cyclin E1 into the nucleolus for multiubiquitylation.

Bhaskaran N, van Drogen F, Ng HF, Kumar R, Ekholm-Reed S, Peter M, Sangfelt O, Reed SI. Bhaskaran N, et al. Among authors: reed si. Mol Cell Biol. 2013 Jan;33(1):85-97. doi: 10.1128/MCB.00288-12. Epub 2012 Oct 29. Mol Cell Biol. 2013. PMID: 23109421 Free PMC article.

6

Detection of low molecular weight derivatives of cyclin E1 is a function of cyclin E1 protein levels in breast cancer.

Spruck C, Sun D, Fiegl H, Marth C, Mueller-Holzner E, Goebel G, Widschwendter M, Reed SI. Spruck C, et al. Among authors: reed si. Cancer Res. 2006 Jul 15;66(14):7355-60. doi: 10.1158/0008-5472.CAN-05-3240. Cancer Res. 2006. PMID: 16849587

7

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line.

Strohmaier H, Spruck CH, Kaiser P, Won KA, Sangfelt O, Reed SI. Strohmaier H, et al. Among authors: reed si. Nature. 2001 Sep 20;413(6853):316-22. doi: 10.1038/35095076. Nature. 2001. PMID: 11565034

8

Ubiquitylation of cyclin E requires the sequential function of SCF complexes containing distinct hCdc4 isoforms.

van Drogen F, Sangfelt O, Malyukova A, Matskova L, Yeh E, Means AR, Reed SI. van Drogen F, et al. Among authors: reed si. Mol Cell. 2006 Jul 7;23(1):37-48. doi: 10.1016/j.molcel.2006.05.020. Mol Cell. 2006. PMID: 16818231 Free article.

9

Cyclin E dysregulation and chromosomal instability in endometrial cancer.

Hubalek MM, Widschwendter A, Erdel M, Gschwendtner A, Fiegl HM, Müller HM, Goebel G, Mueller-Holzner E, Marth C, Spruck CH, Reed SI, Widschwendter M. Hubalek MM, et al. Among authors: reed si. Oncogene. 2004 May 20;23(23):4187-92. doi: 10.1038/sj.onc.1207560. Oncogene. 2004. PMID: 15048079

10

Cks overexpression enhances chemotherapeutic efficacy by overriding DNA damage checkpoints.

del Rincón SV, Widschwendter M, Sun D, Ekholm-Reed S, Tat J, Teixeira LK, Ellederova Z, Grolieres E, Reed SI, Spruck C. del Rincón SV, et al. Among authors: reed si. Oncogene. 2015 Apr 9;34(15):1961-7. doi: 10.1038/onc.2014.137. Epub 2014 May 26. Oncogene. 2015. PMID: 24858038 Free PMC article.

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