von der Lehr N - Search Results

1

FBXW7/hCDC4 is a general tumor suppressor in human cancer.

Akhoondi S, Sun D, von der Lehr N, Apostolidou S, Klotz K, Maljukova A, Cepeda D, Fiegl H, Dafou D, Marth C, Mueller-Holzner E, Corcoran M, Dagnell M, Nejad SZ, Nayer BN, Zali MR, Hansson J, Egyhazi S, Petersson F, Sangfelt P, Nordgren H, Grander D, Reed SI, Widschwendter M, Sangfelt O, Spruck C. Akhoondi S, et al. Among authors: von der lehr n. Cancer Res. 2007 Oct 1;67(19):9006-12. doi: 10.1158/0008-5472.CAN-07-1320. Cancer Res. 2007. PMID: 17909001

2

The tumor suppressor gene hCDC4 is frequently mutated in human T-cell acute lymphoblastic leukemia with functional consequences for Notch signaling.

Malyukova A, Dohda T, von der Lehr N, Akhoondi S, Corcoran M, Heyman M, Spruck C, Grandér D, Lendahl U, Sangfelt O. Malyukova A, et al. Among authors: von der lehr n. Cancer Res. 2007 Jun 15;67(12):5611-6. doi: 10.1158/0008-5472.CAN-06-4381. Cancer Res. 2007. PMID: 17575125

3

Interferon-γ-induced p27KIP1 binds to and targets MYC for proteasome-mediated degradation.

Bahram F, Hydbring P, Tronnersjö S, Zakaria SM, Frings O, Fahlén S, Nilsson H, Goodwin J, von der Lehr N, Su Y, Lüscher B, Castell A, Larsson LG. Bahram F, et al. Among authors: von der lehr n. Oncotarget. 2016 Jan 19;7(3):2837-54. doi: 10.18632/oncotarget.6693. Oncotarget. 2016. PMID: 26701207 Free PMC article.

4

Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformation.

Hydbring P, Bahram F, Su Y, Tronnersjö S, Högstrand K, von der Lehr N, Sharifi HR, Lilischkis R, Hein N, Wu S, Vervoorts J, Henriksson M, Grandien A, Lüscher B, Larsson LG. Hydbring P, et al. Among authors: von der lehr n. Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):58-63. doi: 10.1073/pnas.0900121106. Epub 2009 Dec 4. Proc Natl Acad Sci U S A. 2010. PMID: 19966300 Free PMC article.

5

The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription.

von der Lehr N, Johansson S, Wu S, Bahram F, Castell A, Cetinkaya C, Hydbring P, Weidung I, Nakayama K, Nakayama KI, Söderberg O, Kerppola TK, Larsson LG. von der Lehr N, et al. Mol Cell. 2003 May;11(5):1189-200. doi: 10.1016/s1097-2765(03)00193-x. Mol Cell. 2003. PMID: 12769844 Free article.

6

c-Myc hot spot mutations in lymphomas result in inefficient ubiquitination and decreased proteasome-mediated turnover.

Bahram F, von der Lehr N, Cetinkaya C, Larsson LG. Bahram F, et al. Among authors: von der lehr n. Blood. 2000 Mar 15;95(6):2104-10. Blood. 2000. PMID: 10706881 Free article.

7

Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter.

Wu S, Cetinkaya C, Munoz-Alonso MJ, von der Lehr N, Bahram F, Beuger V, Eilers M, Leon J, Larsson LG. Wu S, et al. Among authors: von der lehr n. Oncogene. 2003 Jan 23;22(3):351-60. doi: 10.1038/sj.onc.1206145. Oncogene. 2003. PMID: 12545156

8

Implication of the ubiquitin/proteasome system in Myc-regulated transcription.

von der Lehr N, Johansson S, Larsson LG. von der Lehr N, et al. Cell Cycle. 2003 Sep-Oct;2(5):403-7. Cell Cycle. 2003. PMID: 12963825 Review.

9

Targeted superantigens for immunotherapy of haematopoietic tumours.

Tötterman TH, Gidlöf C, Ragnarsson L, Högbom E, Lindeberg M, von der Lehr N, Einarsson A, Soegaard M, Kristensson K, Kalland T, Dohlsten M. Tötterman TH, et al. Among authors: von der lehr n. Vox Sang. 1998;74 Suppl 2:483-7. doi: 10.1111/j.1423-0410.1998.tb05461.x. Vox Sang. 1998. PMID: 9704486 Review.

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