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Synthesis, anti-HIV activity, and resistance profiles of ribose modified nucleoside phosphonates.
Bioorg Med Chem Lett. 2007 Dec 15;17(24):6785-9. doi: 10.1016/j.bmcl.2007.10.038. Epub 2007 Oct 17.
Bioorg Med Chem Lett. 2007.
PMID: 18029175
Design, synthesis, and anti-HIV activity of 4'-modified carbocyclic nucleoside phosphonate reverse transcriptase inhibitors.
Boojamra CG, Parrish JP, Sperandio D, Gao Y, Petrakovsky OV, Lee SK, Markevitch DY, Vela JE, Laflamme G, Chen JM, Ray AS, Barron AC, Sparacino ML, Desai MC, Kim CU, Cihlar T, Mackman RL.
Boojamra CG, et al. Among authors: petrakovsky ov.
Bioorg Med Chem. 2009 Feb 15;17(4):1739-46. doi: 10.1016/j.bmc.2008.12.028. Epub 2008 Dec 24.
Bioorg Med Chem. 2009.
PMID: 19179082
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Discovery of GS-9131: Design, synthesis and optimization of amidate prodrugs of the novel nucleoside phosphonate HIV reverse transcriptase (RT) inhibitor GS-9148.
Mackman RL, Ray AS, Hui HC, Zhang L, Birkus G, Boojamra CG, Desai MC, Douglas JL, Gao Y, Grant D, Laflamme G, Lin KY, Markevitch DY, Mishra R, McDermott M, Pakdaman R, Petrakovsky OV, Vela JE, Cihlar T.
Mackman RL, et al. Among authors: petrakovsky ov.
Bioorg Med Chem. 2010 May 15;18(10):3606-17. doi: 10.1016/j.bmc.2010.03.041. Epub 2010 Mar 27.
Bioorg Med Chem. 2010.
PMID: 20409721
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Synthesis and anti-HIV activity of 2'-fluorine modified nucleoside phosphonates: analogs of GS-9148.
Mackman RL, Lin KY, Boojamra CG, Hui H, Douglas J, Grant D, Petrakovsky O, Prasad V, Ray AS, Cihlar T.
Mackman RL, et al. Among authors: petrakovsky o.
Bioorg Med Chem Lett. 2008 Feb 1;18(3):1116-9. doi: 10.1016/j.bmcl.2007.11.126. Epub 2007 Dec 5.
Bioorg Med Chem Lett. 2008.
PMID: 18082402
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Production of hybrid 16-membered macrolides by expressing combinations of polyketide synthase genes in engineered Streptomyces fradiae hosts.
Reeves CD, Ward SL, Revill WP, Suzuki H, Marcus M, Petrakovsky OV, Marquez S, Fu H, Dong SD, Katz L.
Reeves CD, et al. Among authors: petrakovsky ov.
Chem Biol. 2004 Oct;11(10):1465-72. doi: 10.1016/j.chembiol.2004.08.019.
Chem Biol. 2004.
PMID: 15489173
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Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae.
Ward SL, Hu Z, Schirmer A, Reid R, Revill WP, Reeves CD, Petrakovsky OV, Dong SD, Katz L.
Ward SL, et al. Among authors: petrakovsky ov.
Antimicrob Agents Chemother. 2004 Dec;48(12):4703-12. doi: 10.1128/AAC.48.12.4703-4712.2004.
Antimicrob Agents Chemother. 2004.
PMID: 15561847
Free PMC article.
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