Egan DA - Search Results

1

Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1.

Kuijl C, Savage ND, Marsman M, Tuin AW, Janssen L, Egan DA, Ketema M, van den Nieuwendijk R, van den Eeden SJ, Geluk A, Poot A, van der Marel G, Beijersbergen RL, Overkleeft H, Ottenhoff TH, Neefjes J. Kuijl C, et al. Among authors: egan da. Nature. 2007 Nov 29;450(7170):725-30. doi: 10.1038/nature06345. Nature. 2007. PMID: 18046412

2

A Genome-wide multidimensional RNAi screen reveals pathways controlling MHC class II antigen presentation.

Paul P, van den Hoorn T, Jongsma ML, Bakker MJ, Hengeveld R, Janssen L, Cresswell P, Egan DA, van Ham M, Ten Brinke A, Ovaa H, Beijersbergen RL, Kuijl C, Neefjes J. Paul P, et al. Among authors: egan da. Cell. 2011 Apr 15;145(2):268-83. doi: 10.1016/j.cell.2011.03.023. Epub 2011 Mar 31. Cell. 2011. PMID: 21458045 Free article.

3

Identification of F-box only protein 7 as a negative regulator of NF-kappaB signalling.

Kuiken HJ, Egan DA, Laman H, Bernards R, Beijersbergen RL, Dirac AM. Kuiken HJ, et al. Among authors: egan da. J Cell Mol Med. 2012 Sep;16(9):2140-9. doi: 10.1111/j.1582-4934.2012.01524.x. J Cell Mol Med. 2012. PMID: 22212761 Free PMC article.

4

Intra-tumour diversification in colorectal cancer at the single-cell level.

Roerink SF, Sasaki N, Lee-Six H, Young MD, Alexandrov LB, Behjati S, Mitchell TJ, Grossmann S, Lightfoot H, Egan DA, Pronk A, Smakman N, van Gorp J, Anderson E, Gamble SJ, Alder C, van de Wetering M, Campbell PJ, Stratton MR, Clevers H. Roerink SF, et al. Among authors: egan da. Nature. 2018 Apr;556(7702):457-462. doi: 10.1038/s41586-018-0024-3. Epub 2018 Apr 11. Nature. 2018. PMID: 29643510

5

Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation.

le Sage C, Nagel R, Egan DA, Schrier M, Mesman E, Mangiola A, Anile C, Maira G, Mercatelli N, Ciafrè SA, Farace MG, Agami R. le Sage C, et al. Among authors: egan da. EMBO J. 2007 Aug 8;26(15):3699-708. doi: 10.1038/sj.emboj.7601790. Epub 2007 Jul 12. EMBO J. 2007. PMID: 17627278 Free PMC article.

6

A high-throughput pharmaceutical screen identifies compounds with specific toxicity against BRCA2-deficient tumors.

Evers B, Schut E, van der Burg E, Braumuller TM, Egan DA, Holstege H, Edser P, Adams DJ, Wade-Martins R, Bouwman P, Jonkers J. Evers B, et al. Among authors: egan da. Clin Cancer Res. 2010 Jan 1;16(1):99-108. doi: 10.1158/1078-0432.CCR-09-2434. Epub 2009 Dec 15. Clin Cancer Res. 2010. PMID: 20008842 Free PMC article.

7

Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation.

Albers HM, Dong A, van Meeteren LA, Egan DA, Sunkara M, van Tilburg EW, Schuurman K, van Tellingen O, Morris AJ, Smyth SS, Moolenaar WH, Ovaa H. Albers HM, et al. Among authors: egan da. Proc Natl Acad Sci U S A. 2010 Apr 20;107(16):7257-62. doi: 10.1073/pnas.1001529107. Epub 2010 Apr 1. Proc Natl Acad Sci U S A. 2010. PMID: 20360563 Free PMC article.

8

Discovery and optimization of boronic acid based inhibitors of autotaxin.

Albers HM, van Meeteren LA, Egan DA, van Tilburg EW, Moolenaar WH, Ovaa H. Albers HM, et al. Among authors: egan da. J Med Chem. 2010 Jul 8;53(13):4958-67. doi: 10.1021/jm1005012. J Med Chem. 2010. PMID: 20536182

9

High-throughput T-cell epitope discovery through MHC peptide exchange.

Hadrup SR, Toebes M, Rodenko B, Bakker AH, Egan DA, Ovaa H, Schumacher TN. Hadrup SR, et al. Among authors: egan da. Methods Mol Biol. 2009;524:383-405. doi: 10.1007/978-1-59745-450-6_28. Methods Mol Biol. 2009. PMID: 19377960

10

Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening.

Verissimo CS, Overmeer RM, Ponsioen B, Drost J, Mertens S, Verlaan-Klink I, Gerwen BV, van der Ven M, Wetering MV, Egan DA, Bernards R, Clevers H, Bos JL, Snippert HJ. Verissimo CS, et al. Among authors: egan da. Elife. 2016 Nov 15;5:e18489. doi: 10.7554/eLife.18489. Elife. 2016. PMID: 27845624 Free PMC article.

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