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Dramatic increase in naive T cell turnover is linked to loss of naive T cells from old primates.
Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19960-5. doi: 10.1073/pnas.0705905104. Epub 2007 Dec 4.
Proc Natl Acad Sci U S A. 2007.
PMID: 18056811
Free PMC article.
Loss of naive T cells and repertoire constriction predict poor response to vaccination in old primates.
Cicin-Sain L, Smyk-Pearson S, Currier N, Byrd L, Koudelka C, Robinson T, Swarbrick G, Tackitt S, Legasse A, Fischer M, Nikolich-Zugich D, Park B, Hobbs T, Doane CJ, Mori M, Axthelm MK, Lewinsohn DA, Nikolich-Zugich J.
Cicin-Sain L, et al. Among authors: nikolich zugich d.
J Immunol. 2010 Jun 15;184(12):6739-45. doi: 10.4049/jimmunol.0904193. Epub 2010 May 17.
J Immunol. 2010.
PMID: 20483749
Free PMC article.
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Molecular, cellular, and antigen requirements for development of age-associated T cell clonal expansions in vivo.
Messaoudi I, Warner J, Nikolich-Zugich D, Fischer M, Nikolich-Zugich J.
Messaoudi I, et al. Among authors: nikolich zugich d.
J Immunol. 2006 Jan 1;176(1):301-8. doi: 10.4049/jimmunol.176.1.301.
J Immunol. 2006.
PMID: 16365422
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Aging and cytomegalovirus infection differentially and jointly affect distinct circulating T cell subsets in humans.
Wertheimer AM, Bennett MS, Park B, Uhrlaub JL, Martinez C, Pulko V, Currier NL, Nikolich-Žugich D, Kaye J, Nikolich-Žugich J.
Wertheimer AM, et al. Among authors: nikolich zugich d.
J Immunol. 2014 Mar 1;192(5):2143-55. doi: 10.4049/jimmunol.1301721. Epub 2014 Feb 5.
J Immunol. 2014.
PMID: 24501199
Free PMC article.
Clinical Trial.
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Age-related dysregulation in CD8 T cell homeostasis: kinetics of a diversity loss.
LeMaoult J, Messaoudi I, Manavalan JS, Potvin H, Nikolich-Zugich D, Dyall R, Szabo P, Weksler ME, Nikolich-Zugich J.
LeMaoult J, et al. Among authors: nikolich zugich d.
J Immunol. 2000 Sep 1;165(5):2367-73. doi: 10.4049/jimmunol.165.5.2367.
J Immunol. 2000.
PMID: 10946259
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