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Insulin sensitivity, insulin release and glucagon-like peptide-1 levels in persons with impaired fasting glucose and/or impaired glucose tolerance in the EUGENE2 study.
Laakso M, Zilinskaite J, Hansen T, Boesgaard TW, Vänttinen M, Stancáková A, Jansson PA, Pellmé F, Holst JJ, Kuulasmaa T, Hribal ML, Sesti G, Stefan N, Fritsche A, Häring H, Pedersen O, Smith U; EUGENE2 Consortium. Laakso M, et al. Among authors: vanttinen m. Diabetologia. 2008 Mar;51(3):502-11. doi: 10.1007/s00125-007-0899-2. Epub 2007 Dec 14. Diabetologia. 2008. PMID: 18080106
Variants of transcription factor 7-like 2 (TCF7L2) gene predict conversion to type 2 diabetes in the Finnish Diabetes Prevention Study and are associated with impaired glucose regulation and impaired insulin secretion.
Wang J, Kuusisto J, Vänttinen M, Kuulasmaa T, Lindström J, Tuomilehto J, Uusitupa M, Laakso M. Wang J, et al. Among authors: vanttinen m. Diabetologia. 2007 Jun;50(6):1192-200. doi: 10.1007/s00125-007-0656-6. Epub 2007 Apr 17. Diabetologia. 2007. PMID: 17437080
The common SLC30A8 Arg325Trp variant is associated with reduced first-phase insulin release in 846 non-diabetic offspring of type 2 diabetes patients--the EUGENE2 study.
Boesgaard TW, Zilinskaite J, Vänttinen M, Laakso M, Jansson PA, Hammarstedt A, Smith U, Stefan N, Fritsche A, Häring H, Hribal M, Sesti G, Zobel DP, Pedersen O, Hansen T; EUGENE 2 Consortium. Boesgaard TW, et al. Among authors: vanttinen m. Diabetologia. 2008 May;51(5):816-20. doi: 10.1007/s00125-008-0955-6. Epub 2008 Mar 7. Diabetologia. 2008. PMID: 18324385
Single nucleotide polymorphisms of the melanocortin-3 receptor gene are associated with substrate oxidation and first-phase insulin secretion in offspring of type 2 diabetic subjects.
Rutanen J, Pihlajamäki J, Vänttinen M, Salmenniemi U, Ruotsalainen E, Kuulasmaa T, Kainulainen S, Laakso M. Rutanen J, et al. Among authors: vanttinen m. J Clin Endocrinol Metab. 2007 Mar;92(3):1112-7. doi: 10.1210/jc.2006-1201. Epub 2006 Dec 27. J Clin Endocrinol Metab. 2007. PMID: 17192297
A candidate type 2 diabetes polymorphism near the HHEX locus affects acute glucose-stimulated insulin release in European populations: results from the EUGENE2 study.
Staiger H, Stancáková A, Zilinskaite J, Vänttinen M, Hansen T, Marini MA, Hammarstedt A, Jansson PA, Sesti G, Smith U, Pedersen O, Laakso M, Stefan N, Fritsche A, Häring HU. Staiger H, et al. Among authors: vanttinen m. Diabetes. 2008 Feb;57(2):514-7. doi: 10.2337/db07-1254. Epub 2007 Nov 26. Diabetes. 2008. PMID: 18039816
SIRT1 mRNA expression may be associated with energy expenditure and insulin sensitivity.
Rutanen J, Yaluri N, Modi S, Pihlajamäki J, Vänttinen M, Itkonen P, Kainulainen S, Yamamoto H, Lagouge M, Sinclair DA, Elliott P, Westphal C, Auwerx J, Laakso M. Rutanen J, et al. Among authors: vanttinen m. Diabetes. 2010 Apr;59(4):829-35. doi: 10.2337/db09-1191. Epub 2010 Jan 27. Diabetes. 2010. PMID: 20107110 Free PMC article.
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