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Vaccination with a recombinant Saccharomyces cerevisiae expressing a tumor antigen breaks immune tolerance and elicits therapeutic antitumor responses.
Wansley EK, Chakraborty M, Hance KW, Bernstein MB, Boehm AL, Guo Z, Quick D, Franzusoff A, Greiner JW, Schlom J, Hodge JW. Wansley EK, et al. Among authors: franzusoff a. Clin Cancer Res. 2008 Jul 1;14(13):4316-25. doi: 10.1158/1078-0432.CCR-08-0393. Clin Cancer Res. 2008. PMID: 18594015 Free PMC article.
Yeasts encoding tumour antigens in cancer immunotherapy.
Franzusoff A, Duke RC, King TH, Lu Y, Rodell TC. Franzusoff A, et al. Expert Opin Biol Ther. 2005 Apr;5(4):565-75. doi: 10.1517/14712598.5.4.565. Expert Opin Biol Ther. 2005. PMID: 15934834 Review.
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