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Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy.
Reits EA, Hodge JW, Herberts CA, Groothuis TA, Chakraborty M, Wansley EK, Camphausen K, Luiten RM, de Ru AH, Neijssen J, Griekspoor A, Mesman E, Verreck FA, Spits H, Schlom J, van Veelen P, Neefjes JJ. Reits EA, et al. Among authors: wansley ek. J Exp Med. 2006 May 15;203(5):1259-71. doi: 10.1084/jem.20052494. Epub 2006 Apr 24. J Exp Med. 2006. PMID: 16636135 Free PMC article.
The use of chelated radionuclide (samarium-153-ethylenediaminetetramethylenephosphonate) to modulate phenotype of tumor cells and enhance T cell-mediated killing.
Chakraborty M, Wansley EK, Carrasquillo JA, Yu S, Paik CH, Camphausen K, Becker MD, Goeckeler WF, Schlom J, Hodge JW. Chakraborty M, et al. Among authors: wansley ek. Clin Cancer Res. 2008 Jul 1;14(13):4241-9. doi: 10.1158/1078-0432.CCR-08-0335. Clin Cancer Res. 2008. PMID: 18594006 Free PMC article.
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