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A prospective, randomised, placebo-controlled study to identify biomarkers associated with active treatment in psoriatic arthritis: effects of adalimumab treatment on synovial tissue.
van Kuijk AW, Gerlag DM, Vos K, Wolbink G, de Groot M, de Rie MA, Zwinderman AH, Dijkmans BA, Tak PP. van Kuijk AW, et al. Among authors: tak pp. Ann Rheum Dis. 2009 Aug;68(8):1303-9. doi: 10.1136/ard.2008.091389. Epub 2008 Jul 22. Ann Rheum Dis. 2009. PMID: 18647851 Free PMC article. Clinical Trial.
Safety, tolerability, pharmacokinetics, pharmacodynamics and efficacy of the monoclonal antibody ASK8007 blocking osteopontin in patients with rheumatoid arthritis: a randomised, placebo controlled, proof-of-concept study.
Boumans MJ, Houbiers JG, Verschueren P, Ishikura H, Westhovens R, Brouwer E, Rojkovich B, Kelly S, den Adel M, Isaacs J, Jacobs H, Gomez-Reino J, Holtkamp GM, Hastings A, Gerlag DM, Tak PP. Boumans MJ, et al. Among authors: tak pp. Ann Rheum Dis. 2012 Feb;71(2):180-5. doi: 10.1136/annrheumdis-2011-200298. Epub 2011 Sep 14. Ann Rheum Dis. 2012. PMID: 21917822 Clinical Trial.
Inflamed target tissue provides a specific niche for highly expanded T-cell clones in early human autoimmune disease.
Klarenbeek PL, de Hair MJ, Doorenspleet ME, van Schaik BD, Esveldt RE, van de Sande MG, Cantaert T, Gerlag DM, Baeten D, van Kampen AH, Baas F, Tak PP, de Vries N. Klarenbeek PL, et al. Among authors: tak pp. Ann Rheum Dis. 2012 Jun;71(6):1088-93. doi: 10.1136/annrheumdis-2011-200612. Epub 2012 Jan 31. Ann Rheum Dis. 2012. PMID: 22294635
Treatment-specific changes in circulating adipocytokines: a comparison between tumour necrosis factor blockade and glucocorticoid treatment for rheumatoid arthritis.
Klaasen R, Herenius MM, Wijbrandts CA, de Jager W, van Tuyl LH, Nurmohamed MT, Prakken BJ, Gerlag DM, Tak PP. Klaasen R, et al. Among authors: tak pp. Ann Rheum Dis. 2012 Sep;71(9):1510-6. doi: 10.1136/annrheumdis-2011-200646. Epub 2012 Mar 22. Ann Rheum Dis. 2012. PMID: 22440821 Free PMC article.
600 results