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SAR study of 2,3,4,14b-tetrahydro-1H-dibenzo[b,f]pyrido[1,2-d][1,4]oxazepines as progesterone receptor agonists.
Bioorg Med Chem Lett. 2008 Feb 15;18(4):1461-7. doi: 10.1016/j.bmcl.2007.12.065. Epub 2007 Dec 28.
Bioorg Med Chem Lett. 2008.
PMID: 18226526
11-(pyridinylphenyl)steroids--a new class of mixed-profile progesterone agonists/antagonists.
Rewinkel J, Enthoven M, Golstein I, van der Rijst M, Scholten A, van Tilborg M, de Weys D, Wisse J, Hamersma H.
Rewinkel J, et al.
Bioorg Med Chem. 2008 Mar 15;16(6):2753-63. doi: 10.1016/j.bmc.2008.01.010. Epub 2008 Jan 11.
Bioorg Med Chem. 2008.
PMID: 18243712
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1-Aminoisoquinoline as benzamidine isoster in the design and synthesis of orally active thrombin inhibitors.
Rewinkel JB, Lucas H, van Galen PJ, Noach AB, van Dinther TG, Rood AM, Jenneboer AJ, van Boeckel CA.
Rewinkel JB, et al.
Bioorg Med Chem Lett. 1999 Mar 8;9(5):685-90. doi: 10.1016/s0960-894x(99)00069-4.
Bioorg Med Chem Lett. 1999.
PMID: 10201829
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Design, synthesis and testing of amino-bicycloaryl based orally bioavailable thrombin inhibitors.
Rewinkel JB, Lucas H, Smit MJ, Noach AB, van Dinther TG, Rood AM, Jenneboer AJ, van Boeckel CA.
Rewinkel JB, et al.
Bioorg Med Chem Lett. 1999 Oct 4;9(19):2837-42. doi: 10.1016/s0960-894x(99)00483-7.
Bioorg Med Chem Lett. 1999.
PMID: 10522702
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Unique overlap in the prerequisites for thrombin inhibition and oral bioavailability resulting in potent oral antithrombotics.
Adang AE, de Man AP, Vogel GM, Grootenhuis PD, Smit MJ, Peters CA, Visser A, Rewinkel JB, van Dinther T, Lucas H, Kelder J, van Aelst S, Meuleman DG, van Boeckel CA.
Adang AE, et al. Among authors: rewinkel jb.
J Med Chem. 2002 Sep 26;45(20):4419-32. doi: 10.1021/jm011110z.
J Med Chem. 2002.
PMID: 12238922
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Strategies and progress towards the ideal orally active thrombin inhibitor.
Rewinkel JB, Adang AE.
Rewinkel JB, et al.
Curr Pharm Des. 1999 Dec;5(12):1043-75.
Curr Pharm Des. 1999.
PMID: 10607861
Review.
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