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Abeta-globulomers are formed independently of the fibril pathway.
Neurobiol Dis. 2008 May;30(2):212-20. doi: 10.1016/j.nbd.2008.01.010. Epub 2008 Feb 15.
Neurobiol Dis. 2008.
PMID: 18353662
Identification of molecular compounds critical to Alzheimer's-like plaque formation.
Gellermann GP, Ullrich K, Unger C, Fändrich M, Sauter S, Diekmann S.
Gellermann GP, et al.
J Neurosci Res. 2007 Jul;85(9):2037-44. doi: 10.1002/jnr.21311.
J Neurosci Res. 2007.
PMID: 17492785
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Alzheimer-like plaque formation by human macrophages is reduced by fibrillation inhibitors and lovastatin.
Gellermann GP, Ullrich K, Tannert A, Unger C, Habicht G, Sauter SR, Hortschansky P, Horn U, Möllmann U, Decker M, Lehmann J, Fändrich M.
Gellermann GP, et al.
J Mol Biol. 2006 Jul 7;360(2):251-7. doi: 10.1016/j.jmb.2006.05.026. Epub 2006 May 24.
J Mol Biol. 2006.
PMID: 16765377
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Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Abeta protofibrils.
Habicht G, Haupt C, Friedrich RP, Hortschansky P, Sachse C, Meinhardt J, Wieligmann K, Gellermann GP, Brodhun M, Götz J, Halbhuber KJ, Röcken C, Horn U, Fändrich M.
Habicht G, et al. Among authors: gellermann gp.
Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19232-7. doi: 10.1073/pnas.0703793104. Epub 2007 Nov 27.
Proc Natl Acad Sci U S A. 2007.
PMID: 18042730
Free PMC article.
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Raft lipids as common components of human extracellular amyloid fibrils.
Gellermann GP, Appel TR, Tannert A, Radestock A, Hortschansky P, Schroeckh V, Leisner C, Lütkepohl T, Shtrasburg S, Röcken C, Pras M, Linke RP, Diekmann S, Fändrich M.
Gellermann GP, et al.
Proc Natl Acad Sci U S A. 2005 May 3;102(18):6297-302. doi: 10.1073/pnas.0407035102. Epub 2005 Apr 25.
Proc Natl Acad Sci U S A. 2005.
PMID: 15851687
Free PMC article.
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Paired helical filaments contain small amounts of cholesterol, phosphatidylcholine and sphingolipids.
Gellermann GP, Appel TR, Davies P, Diekmann S.
Gellermann GP, et al.
Biol Chem. 2006 Sep;387(9):1267-74. doi: 10.1515/BC.2006.157.
Biol Chem. 2006.
PMID: 16972796
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Establishing a control system using QbD principles.
Kepert JF, Cromwell M, Engler N, Finkler C, Gellermann G, Gennaro L, Harris R, Iverson R, Kelley B, Krummen L, McKnight N, Motchnik P, Schnaible V, Taticek R.
Kepert JF, et al.
Biologicals. 2016 Sep;44(5):319-31. doi: 10.1016/j.biologicals.2016.06.003. Epub 2016 Jul 16.
Biologicals. 2016.
PMID: 27430904
Review.
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Characterization of mAb dimers reveals predominant dimer forms common in therapeutic mAbs.
Plath F, Ringler P, Graff-Meyer A, Stahlberg H, Lauer ME, Rufer AC, Graewert MA, Svergun D, Gellermann G, Finkler C, Stracke JO, Koulov A, Schnaible V.
Plath F, et al.
MAbs. 2016 Jul;8(5):928-40. doi: 10.1080/19420862.2016.1168960. Epub 2016 Mar 31.
MAbs. 2016.
PMID: 27031922
Free PMC article.
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