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Abeta-globulomers are formed independently of the fibril pathway.
Gellermann GP, Byrnes H, Striebinger A, Ullrich K, Mueller R, Hillen H, Barghorn S. Gellermann GP, et al. Neurobiol Dis. 2008 May;30(2):212-20. doi: 10.1016/j.nbd.2008.01.010. Epub 2008 Feb 15. Neurobiol Dis. 2008. PMID: 18353662
Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Abeta protofibrils.
Habicht G, Haupt C, Friedrich RP, Hortschansky P, Sachse C, Meinhardt J, Wieligmann K, Gellermann GP, Brodhun M, Götz J, Halbhuber KJ, Röcken C, Horn U, Fändrich M. Habicht G, et al. Among authors: gellermann gp. Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19232-7. doi: 10.1073/pnas.0703793104. Epub 2007 Nov 27. Proc Natl Acad Sci U S A. 2007. PMID: 18042730 Free PMC article.
Raft lipids as common components of human extracellular amyloid fibrils.
Gellermann GP, Appel TR, Tannert A, Radestock A, Hortschansky P, Schroeckh V, Leisner C, Lütkepohl T, Shtrasburg S, Röcken C, Pras M, Linke RP, Diekmann S, Fändrich M. Gellermann GP, et al. Proc Natl Acad Sci U S A. 2005 May 3;102(18):6297-302. doi: 10.1073/pnas.0407035102. Epub 2005 Apr 25. Proc Natl Acad Sci U S A. 2005. PMID: 15851687 Free PMC article.
Establishing a control system using QbD principles.
Kepert JF, Cromwell M, Engler N, Finkler C, Gellermann G, Gennaro L, Harris R, Iverson R, Kelley B, Krummen L, McKnight N, Motchnik P, Schnaible V, Taticek R. Kepert JF, et al. Biologicals. 2016 Sep;44(5):319-31. doi: 10.1016/j.biologicals.2016.06.003. Epub 2016 Jul 16. Biologicals. 2016. PMID: 27430904 Review.