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Page 1
Severe eczema vaccinatum in a household contact of a smallpox vaccinee.
Vora S, Damon I, Fulginiti V, Weber SG, Kahana M, Stein SL, Gerber SI, Garcia-Houchins S, Lederman E, Hruby D, Collins L, Scott D, Thompson K, Barson JV, Regnery R, Hughes C, Daum RS, Li Y, Zhao H, Smith S, Braden Z, Karem K, Olson V, Davidson W, Trindade G, Bolken T, Jordan R, Tien D, Marcinak J. Vora S, et al. Among authors: bolken t. Clin Infect Dis. 2008 May 15;46(10):1555-61. doi: 10.1086/587668. Clin Infect Dis. 2008. PMID: 18419490
Nonhuman primates are protected from smallpox virus or monkeypox virus challenges by the antiviral drug ST-246.
Huggins J, Goff A, Hensley L, Mucker E, Shamblin J, Wlazlowski C, Johnson W, Chapman J, Larsen T, Twenhafel N, Karem K, Damon IK, Byrd CM, Bolken TC, Jordan R, Hruby D. Huggins J, et al. Among authors: bolken tc. Antimicrob Agents Chemother. 2009 Jun;53(6):2620-5. doi: 10.1128/AAC.00021-09. Epub 2009 Apr 6. Antimicrob Agents Chemother. 2009. PMID: 19349521 Free PMC article.
Tecovirimat for smallpox infections.
Bolken TC, Hruby DE. Bolken TC, et al. Drugs Today (Barc). 2010 Feb;46(2):109-17. doi: 10.1358/dot.2010.46.2.1437244. Drugs Today (Barc). 2010. PMID: 20393639
Efficacy of ST-246 versus lethal poxvirus challenge in immunodeficient mice.
Grosenbach DW, Berhanu A, King DS, Mosier S, Jones KF, Jordan RA, Bolken TC, Hruby DE. Grosenbach DW, et al. Among authors: bolken tc. Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):838-43. doi: 10.1073/pnas.0912134107. Epub 2009 Dec 22. Proc Natl Acad Sci U S A. 2010. PMID: 20080762 Free PMC article.
ST-246 antiviral efficacy in a nonhuman primate monkeypox model: determination of the minimal effective dose and human dose justification.
Jordan R, Goff A, Frimm A, Corrado ML, Hensley LE, Byrd CM, Mucker E, Shamblin J, Bolken TC, Wlazlowski C, Johnson W, Chapman J, Twenhafel N, Tyavanagimatt S, Amantana A, Chinsangaram J, Hruby DE, Huggins J. Jordan R, et al. Antimicrob Agents Chemother. 2009 May;53(5):1817-22. doi: 10.1128/AAC.01596-08. Epub 2009 Feb 17. Antimicrob Agents Chemother. 2009. PMID: 19223621 Free PMC article. Clinical Trial.
Safety and pharmacokinetics of the antiorthopoxvirus compound ST-246 following repeat oral dosing in healthy adult subjects.
Jordan R, Chinsangaram J, Bolken TC, Tyavanagimatt SR, Tien D, Jones KF, Frimm A, Corrado ML, Pickens M, Landis P, Clarke J, Marbury TC, Hruby DE. Jordan R, et al. Among authors: bolken tc. Antimicrob Agents Chemother. 2010 Jun;54(6):2560-6. doi: 10.1128/AAC.01689-09. Epub 2010 Apr 12. Antimicrob Agents Chemother. 2010. PMID: 20385870 Free PMC article. Clinical Trial.
27 results