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Pharmacogenetics of Crohn's disease.
Török HP, Göke B, Konrad A. Török HP, et al. Pharmacogenomics. 2008 Jul;9(7):881-93. doi: 10.2217/14622416.9.7.881. Pharmacogenomics. 2008. PMID: 18597652 Review.
rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants.
Glas J, Seiderer J, Wetzke M, Konrad A, Török HP, Schmechel S, Tonenchi L, Grassl C, Dambacher J, Pfennig S, Maier K, Griga T, Klein W, Epplen JT, Schiemann U, Folwaczny C, Lohse P, Göke B, Ochsenkühn T, Müller-Myhsok B, Folwaczny M, Mussack T, Brand S. Glas J, et al. Among authors: torok hp. PLoS One. 2007 Sep 5;2(9):e819. doi: 10.1371/journal.pone.0000819. PLoS One. 2007. PMID: 17786191 Free PMC article.
The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population.
Glas J, Konrad A, Schmechel S, Dambacher J, Seiderer J, Schroff F, Wetzke M, Roeske D, Török HP, Tonenchi L, Pfennig S, Haller D, Griga T, Klein W, Epplen JT, Folwaczny C, Lohse P, Göke B, Ochsenkühn T, Mussack T, Folwaczny M, Müller-Myhsok B, Brand S. Glas J, et al. Among authors: torok hp. Am J Gastroenterol. 2008 Mar;103(3):682-91. doi: 10.1111/j.1572-0241.2007.01694.x. Epub 2007 Dec 20. Am J Gastroenterol. 2008. PMID: 18162085
rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population.
Glas J, Seiderer J, Pasciuto G, Tillack C, Diegelmann J, Pfennig S, Konrad A, Schmechel S, Wetzke M, Török HP, Stallhofer J, Jürgens M, Griga T, Klein W, Epplen JT, Schiemann U, Mussack T, Lohse P, Göke B, Ochsenkühn T, Folwaczny M, Müller-Myhsok B, Brand S. Glas J, et al. Among authors: torok hp. Am J Gastroenterol. 2009 Mar;104(3):665-72. doi: 10.1038/ajg.2008.65. Epub 2009 Feb 3. Am J Gastroenterol. 2009. PMID: 19262523
Crohn's disease: an immunodeficiency?
Folwaczny C, Glas J, Török HP. Folwaczny C, et al. Among authors: torok hp. Eur J Gastroenterol Hepatol. 2003 Jun;15(6):621-6. doi: 10.1097/00042737-200306000-00007. Eur J Gastroenterol Hepatol. 2003. PMID: 12840672 Review.
61 results