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A mitochondrial protein compendium elucidates complex I disease biology.
Pagliarini DJ, Calvo SE, Chang B, Sheth SA, Vafai SB, Ong SE, Walford GA, Sugiana C, Boneh A, Chen WK, Hill DE, Vidal M, Evans JG, Thorburn DR, Carr SA, Mootha VK. Pagliarini DJ, et al. Cell. 2008 Jul 11;134(1):112-23. doi: 10.1016/j.cell.2008.06.016. Cell. 2008. PMID: 18614015 Free PMC article.
Pptc7 maintains mitochondrial protein content by suppressing receptor-mediated mitophagy.
Niemi NM, Serrano LR, Muehlbauer LK, Balnis C, Kozul KL, Rashan EH, Shishkova E, Schueler KL, Keller MP, Attie AD, Pagan J, Coon JJ, Pagliarini DJ. Niemi NM, et al. Among authors: pagliarini dj. bioRxiv [Preprint]. 2023 Mar 1:2023.02.28.530351. doi: 10.1101/2023.02.28.530351. bioRxiv. 2023. PMID: 36909604 Free PMC article. Updated. Preprint.
Fast and Deep Phosphoproteome Analysis with the Orbitrap Astral Mass Spectrometer.
Lancaster NM, Sinitcyn P, Forny P, Peters-Clarke TM, Fecher C, Smith AJ, Shishkova E, Arrey TN, Pashkova A, Robinson ML, Arp N, Fan J, Hansen J, Galmozzi A, Serrano LR, Rojas J, Gasch AP, Westphall MS, Stewart H, Hock C, Damoc E, Pagliarini DJ, Zabrouskov V, Coon JJ. Lancaster NM, et al. Among authors: pagliarini dj. bioRxiv [Preprint]. 2024 May 16:2023.11.21.568149. doi: 10.1101/2023.11.21.568149. bioRxiv. 2024. PMID: 38045259 Free PMC article. Preprint.
ACAD10 and ACAD11 enable mammalian 4-hydroxy acid lipid catabolism.
Rashan EH, Bartlett AK, Khana DB, Zhang J, Jain R, Smith AJ, Baker ZN, Cook T, Caldwell A, Chevalier AR, Pfleger BF, Yuan P, Amador-Noguez D, Simcox JA, Pagliarini DJ. Rashan EH, et al. Among authors: pagliarini dj. bioRxiv [Preprint]. 2024 Jan 9:2024.01.09.574893. doi: 10.1101/2024.01.09.574893. bioRxiv. 2024. PMID: 38260250 Free PMC article. Preprint.
BRD4-mediated epigenetic regulation of endoplasmic reticulum-mitochondria contact sites is governed by the mitochondrial complex III.
Chen B, Lynn-Nguyen TM, Jadhav P, Halligan BS, Rossiter NJ, Guerra RM, Koshkin S, Koo I, Morlacchi P, Hanna DA, Lin J, Banerjee R, Pagliarini DJ, Patterson AD, Mosalaganti S, Sexton JZ, Calì T, Lyssiotis CA, Shah YM. Chen B, et al. Among authors: pagliarini dj. bioRxiv [Preprint]. 2024 Feb 4:2024.02.02.578646. doi: 10.1101/2024.02.02.578646. bioRxiv. 2024. PMID: 38352460 Free PMC article. Preprint.
PPTC7 maintains mitochondrial protein content by suppressing receptor-mediated mitophagy.
Niemi NM, Serrano LR, Muehlbauer LK, Balnis CE, Wei L, Smith AJ, Kozul KL, Forny M, Connor OM, Rashan EH, Shishkova E, Schueler KL, Keller MP, Attie AD, Friedman JR, Pagan JK, Coon JJ, Pagliarini DJ. Niemi NM, et al. Among authors: pagliarini dj. Nat Commun. 2023 Oct 13;14(1):6431. doi: 10.1038/s41467-023-42069-w. Nat Commun. 2023. PMID: 37833277 Free PMC article.
Small-molecule inhibition of the archetypal UbiB protein COQ8.
Murray NH, Asquith CRM, Fang Z, East MP, Ptak N, Smith RW, Vasta JD, Zimprich CA, Corona CR, Robers MB, Johnson GL, Bingman CA, Pagliarini DJ. Murray NH, et al. Among authors: pagliarini dj. Nat Chem Biol. 2023 Feb;19(2):230-238. doi: 10.1038/s41589-022-01168-3. Epub 2022 Oct 27. Nat Chem Biol. 2023. PMID: 36302899 Free PMC article.
89 results