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Targeted therapy for cancer using PARP inhibitors.
Lord CJ, Ashworth A. Lord CJ, et al. Among authors: ashworth a. Curr Opin Pharmacol. 2008 Aug;8(4):363-9. doi: 10.1016/j.coph.2008.06.016. Curr Opin Pharmacol. 2008. PMID: 18644251 Review.
Functions of the BRCA1 and BRCA2 genes.
Bertwistle D, Ashworth A. Bertwistle D, et al. Among authors: ashworth a. Curr Opin Genet Dev. 1998 Feb;8(1):14-20. doi: 10.1016/s0959-437x(98)80056-7. Curr Opin Genet Dev. 1998. PMID: 9529600 Review.
Phenotypic effects of heterozygosity for a BRCA2 mutation.
Warren M, Lord CJ, Masabanda J, Griffin D, Ashworth A. Warren M, et al. Among authors: ashworth a. Hum Mol Genet. 2003 Oct 15;12(20):2645-56. doi: 10.1093/hmg/ddg277. Epub 2003 Aug 19. Hum Mol Genet. 2003. PMID: 12928478
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy.
Farmer H, McCabe N, Lord CJ, Tutt AN, Johnson DA, Richardson TB, Santarosa M, Dillon KJ, Hickson I, Knights C, Martin NM, Jackson SP, Smith GC, Ashworth A. Farmer H, et al. Among authors: ashworth a. Nature. 2005 Apr 14;434(7035):917-21. doi: 10.1038/nature03445. Nature. 2005. PMID: 15829967 Free article.
BRCA1 and BRCA2 as ovarian cancer susceptibility genes.
Sowter HM, Ashworth A. Sowter HM, et al. Among authors: ashworth a. Carcinogenesis. 2005 Oct;26(10):1651-6. doi: 10.1093/carcin/bgi136. Epub 2005 May 25. Carcinogenesis. 2005. PMID: 15917310
Targeting the DNA repair defect of BRCA tumours.
Turner N, Tutt A, Ashworth A. Turner N, et al. Among authors: ashworth a. Curr Opin Pharmacol. 2005 Aug;5(4):388-93. doi: 10.1016/j.coph.2005.03.006. Curr Opin Pharmacol. 2005. PMID: 15955736 Review.
825 results