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Drug-susceptible HIV-1 infection despite intermittent fixed-dose combination tenofovir/emtricitabine as prophylaxis is associated with low-level viremia, delayed seroconversion, and an attenuated clinical course.
Prada N, Davis B, Jean-Pierre P, La Roche M, Duh FM, Carrington M, Poles M, Mehandru S, Mohri H, Markowitz M. Prada N, et al. Among authors: carrington m. J Acquir Immune Defic Syndr. 2008 Oct 1;49(2):117-22. doi: 10.1097/QAI.0b013e3181869a9b. J Acquir Immune Defic Syndr. 2008. PMID: 18769360 Free PMC article.
Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection.
Brumme ZL, Brumme CJ, Carlson J, Streeck H, John M, Eichbaum Q, Block BL, Baker B, Kadie C, Markowitz M, Jessen H, Kelleher AD, Rosenberg E, Kaldor J, Yuki Y, Carrington M, Allen TM, Mallal S, Altfeld M, Heckerman D, Walker BD. Brumme ZL, et al. Among authors: carrington m. J Virol. 2008 Sep;82(18):9216-27. doi: 10.1128/JVI.01041-08. Epub 2008 Jul 9. J Virol. 2008. PMID: 18614631 Free PMC article.
Genotypic and functional impact of HIV-1 adaptation to its host population during the North American epidemic.
Cotton LA, Kuang XT, Le AQ, Carlson JM, Chan B, Chopera DR, Brumme CJ, Markle TJ, Martin E, Shahid A, Anmole G, Mwimanzi P, Nassab P, Penney KA, Rahman MA, Milloy MJ, Schechter MT, Markowitz M, Carrington M, Walker BD, Wagner T, Buchbinder S, Fuchs J, Koblin B, Mayer KH, Harrigan PR, Brockman MA, Poon AF, Brumme ZL. Cotton LA, et al. Among authors: carrington m. PLoS Genet. 2014 Apr 24;10(4):e1004295. doi: 10.1371/journal.pgen.1004295. eCollection 2014 Apr. PLoS Genet. 2014. PMID: 24762668 Free PMC article.
Population-Level Immune-Mediated Adaptation in HIV-1 Polymerase during the North American Epidemic.
Kinloch NN, MacMillan DR, Le AQ, Cotton LA, Bangsberg DR, Buchbinder S, Carrington M, Fuchs J, Harrigan PR, Koblin B, Kushel M, Markowitz M, Mayer K, Milloy MJ, Schechter MT, Wagner T, Walker BD, Carlson JM, Poon AF, Brumme ZL. Kinloch NN, et al. Among authors: carrington m. J Virol. 2015 Nov 11;90(3):1244-58. doi: 10.1128/JVI.02353-15. Print 2016 Feb 1. J Virol. 2015. PMID: 26559841 Free PMC article.
Broadly reactive human CD8 T cells that recognize an epitope conserved between VZV, HSV and EBV.
Chiu C, McCausland M, Sidney J, Duh FM, Rouphael N, Mehta A, Mulligan M, Carrington M, Wieland A, Sullivan NL, Weinberg A, Levin MJ, Pulendran B, Peters B, Sette A, Ahmed R. Chiu C, et al. Among authors: carrington m. PLoS Pathog. 2014 Mar 27;10(3):e1004008. doi: 10.1371/journal.ppat.1004008. eCollection 2014 Mar. PLoS Pathog. 2014. PMID: 24675761 Free PMC article.
Early immune adaptation in HIV-1 revealed by population-level approaches.
Martin E, Carlson JM, Le AQ, Chopera DR, McGovern R, Rahman MA, Ng C, Jessen H, Kelleher AD, Markowitz M, Allen TM, Milloy MJ, Carrington M, Wainberg MA, Brumme ZL. Martin E, et al. Among authors: carrington m. Retrovirology. 2014 Aug 29;11:64. doi: 10.1186/s12977-014-0064-1. Retrovirology. 2014. PMID: 25212686 Free PMC article.
810 results