Lannutti BJ - Search Results

1

Incomplete restoration of Mpl expression in the mpl-/- mouse produces partial correction of the stem cell-repopulating defect and paradoxical thrombocytosis.

Lannutti BJ, Epp A, Roy J, Chen J, Josephson NC. Lannutti BJ, et al. Blood. 2009 Feb 19;113(8):1778-85. doi: 10.1182/blood-2007-11-124859. Epub 2008 Sep 16. Blood. 2009. PMID: 18796624 Free PMC article.

2

Lyn tyrosine kinase regulates thrombopoietin-induced proliferation of hematopoietic cell lines and primary megakaryocytic progenitors.

Lannutti BJ, Drachman JG. Lannutti BJ, et al. Blood. 2004 May 15;103(10):3736-43. doi: 10.1182/blood-2003-10-3566. Epub 2004 Jan 15. Blood. 2004. PMID: 14726379 Free article.

3

Induction of polyploidization in leukemic cell lines and primary bone marrow by Src kinase inhibitor SU6656.

Lannutti BJ, Blake N, Gandhi MJ, Reems JA, Drachman JG. Lannutti BJ, et al. Blood. 2005 May 15;105(10):3875-8. doi: 10.1182/blood-2004-10-3934. Epub 2005 Jan 27. Blood. 2005. PMID: 15677565 Free PMC article.

4

A novel strategy for generating platelet-like fragments from megakaryocytic cell lines and human progenitor cells.

Gandhi MJ, Drachman JG, Reems JA, Thorning D, Lannutti BJ. Gandhi MJ, et al. Among authors: lannutti bj. Blood Cells Mol Dis. 2005 Jul-Aug;35(1):70-3. doi: 10.1016/j.bcmd.2005.04.002. Blood Cells Mol Dis. 2005. PMID: 15923131

5

Increased megakaryocytopoiesis in Lyn-deficient mice.

Lannutti BJ, Minear J, Blake N, Drachman JG. Lannutti BJ, et al. Oncogene. 2006 Jun 1;25(23):3316-24. doi: 10.1038/sj.onc.1209351. Epub 2006 Jan 16. Oncogene. 2006. PMID: 16418722

6

PI3Kδ inhibitor, GS-1101 (CAL-101), attenuates pathway signaling, induces apoptosis, and overcomes signals from the microenvironment in cellular models of Hodgkin lymphoma.

Meadows SA, Vega F, Kashishian A, Johnson D, Diehl V, Miller LL, Younes A, Lannutti BJ. Meadows SA, et al. Among authors: lannutti bj. Blood. 2012 Feb 23;119(8):1897-900. doi: 10.1182/blood-2011-10-386763. Epub 2011 Dec 30. Blood. 2012. PMID: 22210877 Free article.

7

CAL-101, a p110delta selective phosphatidylinositol-3-kinase inhibitor for the treatment of B-cell malignancies, inhibits PI3K signaling and cellular viability.

Lannutti BJ, Meadows SA, Herman SE, Kashishian A, Steiner B, Johnson AJ, Byrd JC, Tyner JW, Loriaux MM, Deininger M, Druker BJ, Puri KD, Ulrich RG, Giese NA. Lannutti BJ, et al. Blood. 2011 Jan 13;117(2):591-4. doi: 10.1182/blood-2010-03-275305. Epub 2010 Oct 19. Blood. 2011. PMID: 20959606 Free PMC article.

8

Identification and activation of Src family kinases in primary megakaryocytes.

Lannutti BJ, Shim MH, Blake N, Reems JA, Drachman JG. Lannutti BJ, et al. Exp Hematol. 2003 Dec;31(12):1268-74. doi: 10.1016/j.exphem.2003.09.009. Exp Hematol. 2003. PMID: 14662334 Free article.

9

Expression of the GPI-anchored receptor Prv-1 enhances thrombopoietin and IL-3-induced proliferation in hematopoietic cell lines.

Dillon M, Minear J, Johnson J, Lannutti BJ. Dillon M, et al. Among authors: lannutti bj. Leuk Res. 2008 May;32(5):811-9. doi: 10.1016/j.leukres.2007.09.018. Epub 2007 Nov 5. Leuk Res. 2008. PMID: 17980909

10

Idelalisib, an inhibitor of phosphatidylinositol 3-kinase p110δ, for relapsed/refractory chronic lymphocytic leukemia.

Brown JR, Byrd JC, Coutre SE, Benson DM, Flinn IW, Wagner-Johnston ND, Spurgeon SE, Kahl BS, Bello C, Webb HK, Johnson DM, Peterman S, Li D, Jahn TM, Lannutti BJ, Ulrich RG, Yu AS, Miller LL, Furman RR. Brown JR, et al. Among authors: lannutti bj. Blood. 2014 May 29;123(22):3390-7. doi: 10.1182/blood-2013-11-535047. Epub 2014 Mar 10. Blood. 2014. PMID: 24615777 Free PMC article. Clinical Trial.

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