De Keersmaecker K - Search Results

1

Heterogeneous patterns of amplification of the NUP214-ABL1 fusion gene in T-cell acute lymphoblastic leukemia.

Graux C, Stevens-Kroef M, Lafage M, Dastugue N, Harrison CJ, Mugneret F, Bahloula K, Struski S, Grégoire MJ, Nadal N, Lippert E, Taviaux S, Simons A, Kuiper RP, Moorman AV, Barber K, Bosly A, Michaux L, Vandenberghe P, Lahortiga I, De Keersmaecker K, Wlodarska I, Cools J, Hagemeijer A, Poirel HA; Groupe Francophone de Cytogénétique Hématologique; Belgian Cytogenetic Group for Hematology and Oncology. Graux C, et al. Among authors: de keersmaecker k. Leukemia. 2009 Jan;23(1):125-33. doi: 10.1038/leu.2008.278. Epub 2008 Oct 16. Leukemia. 2009. PMID: 18923437

2

Fusion of EML1 to ABL1 in T-cell acute lymphoblastic leukemia with cryptic t(9;14)(q34;q32).

De Keersmaecker K, Graux C, Odero MD, Mentens N, Somers R, Maertens J, Wlodarska I, Vandenberghe P, Hagemeijer A, Marynen P, Cools J. De Keersmaecker K, et al. Blood. 2005 Jun 15;105(12):4849-52. doi: 10.1182/blood-2004-12-4897. Epub 2005 Feb 15. Blood. 2005. PMID: 15713800 Free article.

3

Genetic insights in the pathogenesis of T-cell acute lymphoblastic leukemia.

De Keersmaecker K, Marynen P, Cools J. De Keersmaecker K, et al. Haematologica. 2005 Aug;90(8):1116-27. Haematologica. 2005. PMID: 16079112 Review.

4

Chronic myeloproliferative disorders: a tyrosine kinase tale.

De Keersmaecker K, Cools J. De Keersmaecker K, et al. Leukemia. 2006 Feb;20(2):200-5. doi: 10.1038/sj.leu.2404064. Leukemia. 2006. PMID: 16341034 Review.

5

Transition from EML1-ABL1 to NUP214-ABL1 positivity in a patient with acute T-lymphoblastic leukemia.

De Keersmaecker K, Lahortiga I, Graux C, Marynen P, Maertens J, Cools J, Vandenberghe P. De Keersmaecker K, et al. Leukemia. 2006 Dec;20(12):2202-4. doi: 10.1038/sj.leu.2404425. Epub 2006 Oct 5. Leukemia. 2006. PMID: 17024111 No abstract available.

6

Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia.

Lahortiga I, De Keersmaecker K, Van Vlierberghe P, Graux C, Cauwelier B, Lambert F, Mentens N, Beverloo HB, Pieters R, Speleman F, Odero MD, Bauters M, Froyen G, Marynen P, Vandenberghe P, Wlodarska I, Meijerink JP, Cools J. Lahortiga I, et al. Among authors: de keersmaecker k. Nat Genet. 2007 May;39(5):593-5. doi: 10.1038/ng2025. Epub 2007 Apr 15. Nat Genet. 2007. PMID: 17435759

7

In vitro validation of gamma-secretase inhibitors alone or in combination with other anti-cancer drugs for the treatment of T-cell acute lymphoblastic leukemia.

De Keersmaecker K, Lahortiga I, Mentens N, Folens C, Van Neste L, Bekaert S, Vandenberghe P, Odero MD, Marynen P, Cools J. De Keersmaecker K, et al. Haematologica. 2008 Apr;93(4):533-42. doi: 10.3324/haematol.11894. Epub 2008 Mar 5. Haematologica. 2008. PMID: 18322257 Free article.

8

Kinase activation and transformation by NUP214-ABL1 is dependent on the context of the nuclear pore.

De Keersmaecker K, Rocnik JL, Bernad R, Lee BH, Leeman D, Gielen O, Verachtert H, Folens C, Munck S, Marynen P, Fornerod M, Gilliland DG, Cools J. De Keersmaecker K, et al. Mol Cell. 2008 Jul 11;31(1):134-42. doi: 10.1016/j.molcel.2008.05.005. Mol Cell. 2008. PMID: 18614052 Free article.

9

Intrinsic differences between the catalytic properties of the oncogenic NUP214-ABL1 and BCR-ABL1 fusion protein kinases.

De Keersmaecker K, Versele M, Cools J, Superti-Furga G, Hantschel O. De Keersmaecker K, et al. Leukemia. 2008 Dec;22(12):2208-16. doi: 10.1038/leu.2008.242. Epub 2008 Sep 11. Leukemia. 2008. PMID: 18784740

10

ABL1 fusions in T-cell acute lymphoblastic leukemia.

De Keersmaecker K. De Keersmaecker K. Verh K Acad Geneeskd Belg. 2008;70(4):245-55. Verh K Acad Geneeskd Belg. 2008. PMID: 19166098 Review.

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