de Bruin M - Search Results

1

High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs.

Rottenberg S, Jaspers JE, Kersbergen A, van der Burg E, Nygren AO, Zander SA, Derksen PW, de Bruin M, Zevenhoven J, Lau A, Boulter R, Cranston A, O'Connor MJ, Martin NM, Borst P, Jonkers J. Rottenberg S, et al. Among authors: de bruin m. Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):17079-84. doi: 10.1073/pnas.0806092105. Epub 2008 Oct 29. Proc Natl Acad Sci U S A. 2008. PMID: 18971340 Free PMC article.

2

Selective inhibition of BRCA2-deficient mammary tumor cell growth by AZD2281 and cisplatin.

Evers B, Drost R, Schut E, de Bruin M, van der Burg E, Derksen PW, Holstege H, Liu X, van Drunen E, Beverloo HB, Smith GC, Martin NM, Lau A, O'Connor MJ, Jonkers J. Evers B, et al. Among authors: de bruin m. Clin Cancer Res. 2008 Jun 15;14(12):3916-25. doi: 10.1158/1078-0432.CCR-07-4953. Clin Cancer Res. 2008. PMID: 18559613 Free article.

3

Fibroblast growth factor receptor 1-transformed mammary epithelial cells are dependent on RSK activity for growth and survival.

Xian W, Pappas L, Pandya D, Selfors LM, Derksen PW, de Bruin M, Gray NS, Jonkers J, Rosen JM, Brugge JS. Xian W, et al. Among authors: de bruin m. Cancer Res. 2009 Mar 15;69(6):2244-51. doi: 10.1158/0008-5472.CAN-08-3398. Epub 2009 Mar 3. Cancer Res. 2009. PMID: 19258500

4

Suppression of tumor growth, invasion and angiogenesis of human gastric cancer by adenovirus-mediated expression of NK4.

Heideman DA, van Beusechem VW, Bloemena E, Snijders PJ, Craanen ME, Offerhaus GJ, Derksen PW, de Bruin M, Witlox MA, Molenaar B, Meijer CJ, Gerritsen WR. Heideman DA, et al. Among authors: de bruin m. J Gene Med. 2004 Mar;6(3):317-27. doi: 10.1002/jgm.523. J Gene Med. 2004. PMID: 15026993

5

Therapeutic potential of the dual-targeted TAS-102 formulation in the treatment of gastrointestinal malignancies.

Temmink OH, Emura T, de Bruin M, Fukushima M, Peters GJ. Temmink OH, et al. Among authors: de bruin m. Cancer Sci. 2007 Jun;98(6):779-89. doi: 10.1111/j.1349-7006.2007.00477.x. Epub 2007 Apr 18. Cancer Sci. 2007. PMID: 17441963 Free article. Review.

6

Determinants of trifluorothymidine sensitivity and metabolism in colon and lung cancer cells.

Temmink OH, de Bruin M, Comijn EM, Fukushima M, Peters GJ. Temmink OH, et al. Among authors: de bruin m. Anticancer Drugs. 2005 Mar;16(3):285-92. doi: 10.1097/00001813-200503000-00007. Anticancer Drugs. 2005. PMID: 15711180

7

Activity and substrate specificity of pyrimidine phosphorylases and their role in fluoropyrimidine sensitivity in colon cancer cell lines.

Temmink OH, de Bruin M, Turksma AW, Cricca S, Laan AC, Peters GJ. Temmink OH, et al. Among authors: de bruin m. Int J Biochem Cell Biol. 2007;39(3):565-75. doi: 10.1016/j.biocel.2006.10.009. Epub 2006 Oct 21. Int J Biochem Cell Biol. 2007. PMID: 17098463

8

Reversal of resistance by GF120918 in cell lines expressing the ABC half-transporter, MXR.

de Bruin M, Miyake K, Litman T, Robey R, Bates SE. de Bruin M, et al. Cancer Lett. 1999 Nov 15;146(2):117-26. doi: 10.1016/s0304-3835(99)00182-2. Cancer Lett. 1999. PMID: 10656616

9

The effect of fluoropyrimidines with or without thymidine phosphorylase inhibitor on the expression of thymidine phosphorylase.

De Bruin M, Van Capel T, Smid K, Fukushima M, Hoekman K, Pinedo HM, Peters GJ. De Bruin M, et al. Eur J Pharmacol. 2004 May 3;491(2-3):93-9. doi: 10.1016/j.ejphar.2004.03.025. Eur J Pharmacol. 2004. PMID: 15140625

10

Sulfasalazine down-regulates the expression of the angiogenic factors platelet-derived endothelial cell growth factor/thymidine phosphorylase and interleukin-8 in human monocytic-macrophage THP1 and U937 cells.

de Bruin M, Peters GJ, Oerlemans R, Assaraf YG, Masterson AJ, Adema AD, Dijkmans BA, Pinedo HM, Jansen G. de Bruin M, et al. Mol Pharmacol. 2004 Oct;66(4):1054-60. doi: 10.1124/mol.104.000315. Epub 2004 Jul 21. Mol Pharmacol. 2004. PMID: 15269287

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