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Mycobacterial secretion systems ESX-1 and ESX-5 play distinct roles in host cell death and inflammasome activation.
Abdallah AM, Bestebroer J, Savage ND, de Punder K, van Zon M, Wilson L, Korbee CJ, van der Sar AM, Ottenhoff TH, van der Wel NN, Bitter W, Peters PJ. Abdallah AM, et al. Among authors: van der wel nn, van der sar am, van zon m. J Immunol. 2011 Nov 1;187(9):4744-53. doi: 10.4049/jimmunol.1101457. Epub 2011 Sep 28. J Immunol. 2011. PMID: 21957139
Direct visualization by cryo-EM of the mycobacterial capsular layer: a labile structure containing ESX-1-secreted proteins.
Sani M, Houben EN, Geurtsen J, Pierson J, de Punder K, van Zon M, Wever B, Piersma SR, Jiménez CR, Daffé M, Appelmelk BJ, Bitter W, van der Wel N, Peters PJ. Sani M, et al. Among authors: van der wel n, van zon m. PLoS Pathog. 2010 Mar 5;6(3):e1000794. doi: 10.1371/journal.ppat.1000794. PLoS Pathog. 2010. PMID: 20221442 Free PMC article.
ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria.
Houben D, Demangel C, van Ingen J, Perez J, Baldeón L, Abdallah AM, Caleechurn L, Bottai D, van Zon M, de Punder K, van der Laan T, Kant A, Bossers-de Vries R, Willemsen P, Bitter W, van Soolingen D, Brosch R, van der Wel N, Peters PJ. Houben D, et al. Among authors: van ingen j, van soolingen d, van der wel n, van zon m, van der laan t. Cell Microbiol. 2012 Aug;14(8):1287-98. doi: 10.1111/j.1462-5822.2012.01799.x. Epub 2012 May 8. Cell Microbiol. 2012. PMID: 22524898
Mannan core branching of lipo(arabino)mannan is required for mycobacterial virulence in the context of innate immunity.
Stoop EJ, Mishra AK, Driessen NN, van Stempvoort G, Bouchier P, Verboom T, van Leeuwen LM, Sparrius M, Raadsen SA, van Zon M, van der Wel NN, Besra GS, Geurtsen J, Bitter W, Appelmelk BJ, van der Sar AM. Stoop EJ, et al. Among authors: van zon m. Cell Microbiol. 2013 Dec;15(12):2093-108. doi: 10.1111/cmi.12175. Epub 2013 Aug 22. Cell Microbiol. 2013. PMID: 23902464 Free PMC article.
IL-1R1-Dependent Signals Improve Control of Cytosolic Virulent Mycobacteria In Vivo.
van der Niet S, van Zon M, de Punder K, Grootemaat A, Rutten S, Moorlag SJCFM, Houben D, van der Sar AM, Bitter W, Brosch R, Hernandez Pando R, Pena MT, Peters PJ, Reits EA, Mayer-Barber KD, van der Wel NN. van der Niet S, et al. Among authors: van zon m. mSphere. 2021 May 5;6(3):e00153-21. doi: 10.1128/mSphere.00153-21. mSphere. 2021. PMID: 33952660 Free PMC article.
Evasion of peptide, but not lipid antigen presentation, through pathogen-induced dendritic cell maturation.
Hava DL, van der Wel N, Cohen N, Dascher CC, Houben D, León L, Agarwal S, Sugita M, van Zon M, Kent SC, Shams H, Peters PJ, Brenner MB. Hava DL, et al. Among authors: van der wel n, van zon m. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11281-6. doi: 10.1073/pnas.0804681105. Epub 2008 Aug 6. Proc Natl Acad Sci U S A. 2008. PMID: 18685099 Free PMC article.
Autotaxin impedes anti-tumor immunity by suppressing chemotaxis and tumor infiltration of CD8+ T cells.
Matas-Rico E, Frijlink E, van der Haar Àvila I, Menegakis A, van Zon M, Morris AJ, Koster J, Salgado-Polo F, de Kivit S, Lança T, Mazzocca A, Johnson Z, Haanen J, Schumacher TN, Perrakis A, Verbrugge I, van den Berg JH, Borst J, Moolenaar WH. Matas-Rico E, et al. Among authors: van zon m. Cell Rep. 2021 Nov 16;37(7):110013. doi: 10.1016/j.celrep.2021.110013. Cell Rep. 2021. PMID: 34788605 Free PMC article.
Tumor infiltrating lymphocytes (TIL) therapy in metastatic melanoma: boosting of neoantigen-specific T cell reactivity and long-term follow-up.
van den Berg JH, Heemskerk B, van Rooij N, Gomez-Eerland R, Michels S, van Zon M, de Boer R, Bakker NAM, Jorritsma-Smit A, van Buuren MM, Kvistborg P, Spits H, Schotte R, Mallo H, Karger M, van der Hage JA, Wouters MWJM, Pronk LM, Geukes Foppen MH, Blank CU, Beijnen JH, Nuijen B, Schumacher TN, Haanen JBAG. van den Berg JH, et al. Among authors: van zon m. J Immunother Cancer. 2020 Aug;8(2):e000848. doi: 10.1136/jitc-2020-000848. J Immunother Cancer. 2020. PMID: 32753545 Free PMC article. Clinical Trial.
18 results