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CS1 promotes multiple myeloma cell adhesion, clonogenic growth, and tumorigenicity via c-maf-mediated interactions with bone marrow stromal cells.
Tai YT, Soydan E, Song W, Fulciniti M, Kim K, Hong F, Li XF, Burger P, Rumizen MJ, Nahar S, Podar K, Hideshima T, Munshi NC, Tonon G, Carrasco RD, Afar DE, Anderson KC. Tai YT, et al. Among authors: tonon g. Blood. 2009 Apr 30;113(18):4309-18. doi: 10.1182/blood-2008-10-183772. Epub 2009 Feb 4. Blood. 2009. PMID: 19196658 Free PMC article. Retracted.
High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients.
Carrasco DR, Tonon G, Huang Y, Zhang Y, Sinha R, Feng B, Stewart JP, Zhan F, Khatry D, Protopopova M, Protopopov A, Sukhdeo K, Hanamura I, Stephens O, Barlogie B, Anderson KC, Chin L, Shaughnessy JD Jr, Brennan C, Depinho RA. Carrasco DR, et al. Among authors: tonon g. Cancer Cell. 2006 Apr;9(4):313-25. doi: 10.1016/j.ccr.2006.03.019. Cancer Cell. 2006. PMID: 16616336 Free article.
The small-molecule VEGF receptor inhibitor pazopanib (GW786034B) targets both tumor and endothelial cells in multiple myeloma.
Podar K, Tonon G, Sattler M, Tai YT, Legouill S, Yasui H, Ishitsuka K, Kumar S, Kumar R, Pandite LN, Hideshima T, Chauhan D, Anderson KC. Podar K, et al. Among authors: tonon g. Proc Natl Acad Sci U S A. 2006 Dec 19;103(51):19478-83. doi: 10.1073/pnas.0609329103. Epub 2006 Dec 12. Proc Natl Acad Sci U S A. 2006. PMID: 17164332 Free PMC article.
The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis.
Carrasco DR, Sukhdeo K, Protopopova M, Sinha R, Enos M, Carrasco DE, Zheng M, Mani M, Henderson J, Pinkus GS, Munshi N, Horner J, Ivanova EV, Protopopov A, Anderson KC, Tonon G, DePinho RA. Carrasco DR, et al. Among authors: tonon g. Cancer Cell. 2007 Apr;11(4):349-60. doi: 10.1016/j.ccr.2007.02.015. Cancer Cell. 2007. PMID: 17418411 Free PMC article.
Moving toward individualized cancer therapies.
Tonon G, Anderson KC. Tonon G, et al. Clin Cancer Res. 2008 Aug 1;14(15):4682-4. doi: 10.1158/1078-0432.CCR-08-1134. Clin Cancer Res. 2008. PMID: 18676734 Review.
Targeting PKC: a novel role for beta-catenin in ER stress and apoptotic signaling.
Raab MS, Breitkreutz I, Tonon G, Zhang J, Hayden PJ, Nguyen T, Fruehauf JH, Lin BK, Chauhan D, Hideshima T, Munshi NC, Anderson KC, Podar K. Raab MS, et al. Among authors: tonon g. Blood. 2009 Feb 12;113(7):1513-21. doi: 10.1182/blood-2008-05-157040. Epub 2008 Nov 18. Blood. 2009. PMID: 19018094 Free PMC article.
The selective adhesion molecule inhibitor Natalizumab decreases multiple myeloma cell growth in the bone marrow microenvironment: therapeutic implications.
Podar K, Zimmerhackl A, Fulciniti M, Tonon G, Hainz U, Tai YT, Vallet S, Halama N, Jäger D, Olson DL, Sattler M, Chauhan D, Anderson KC. Podar K, et al. Among authors: tonon g. Br J Haematol. 2011 Nov;155(4):438-48. doi: 10.1111/j.1365-2141.2011.08864.x. Epub 2011 Sep 19. Br J Haematol. 2011. PMID: 21923653 Free article.
198 results