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A Quantitative Systems Pharmacology Model Describing the Cellular Kinetic-Pharmacodynamic Relationship for a Live Biotherapeutic Product to Support Microbiome Drug Development.
Renardy M, Prokopienko AJ, Maxwell JR, Flusberg DA, Makaryan S, Selimkhanov J, Vakilynejad M, Subramanian K, Wille L. Renardy M, et al. Among authors: wille l. Clin Pharmacol Ther. 2023 Sep;114(3):633-643. doi: 10.1002/cpt.2952. Epub 2023 Jun 2. Clin Pharmacol Ther. 2023. PMID: 37218407
Programmable soft valves for digital and analog control.
Decker CJ, Jiang HJ, Nemitz MP, Root SE, Rajappan A, Alvarez JT, Tracz J, Wille L, Preston DJ, Whitesides GM. Decker CJ, et al. Among authors: wille l. Proc Natl Acad Sci U S A. 2022 Oct 4;119(40):e2205922119. doi: 10.1073/pnas.2205922119. Epub 2022 Sep 26. Proc Natl Acad Sci U S A. 2022. PMID: 36161907 Free PMC article.
A systems pharmacology model for gene therapy in sickle cell disease.
Zheng B, Wille L, Peppel K, Hagen D, Matteson A, Ahlers J, Schaff J, Hua F, Yuraszeck T, Cobbina E, Apgar JF, Burke JM, Roberts J, Das R. Zheng B, et al. Among authors: wille l. CPT Pharmacometrics Syst Pharmacol. 2021 Jul;10(7):696-708. doi: 10.1002/psp4.12638. Epub 2021 Jun 17. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 34139105 Free PMC article.
160 results