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Discovery of N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (BMS-777607), a selective and orally efficacious inhibitor of the Met kinase superfamily.
Schroeder GM, An Y, Cai ZW, Chen XT, Clark C, Cornelius LA, Dai J, Gullo-Brown J, Gupta A, Henley B, Hunt JT, Jeyaseelan R, Kamath A, Kim K, Lippy J, Lombardo LJ, Manne V, Oppenheimer S, Sack JS, Schmidt RJ, Shen G, Stefanski K, Tokarski JS, Trainor GL, Wautlet BS, Wei D, Williams DK, Zhang Y, Zhang Y, Fargnoli J, Borzilleri RM. Schroeder GM, et al. Among authors: clark c. J Med Chem. 2009 Mar 12;52(5):1251-4. doi: 10.1021/jm801586s. J Med Chem. 2009. PMID: 19260711
Discovery of N-propylurea 3-benzylpiperidines as selective CC chemokine receptor-3 (CCR3) antagonists.
Varnes JG, Gardner DS, Santella JB 3rd, Duncia JV, Estrella M, Watson PS, Clark CM, Ko SS, Welch P, Covington M, Stowell N, Wadman E, Davies P, Solomon K, Newton RC, Trainor GL, Decicco CP, Wacker DA. Varnes JG, et al. Among authors: clark cm. Bioorg Med Chem Lett. 2004 Apr 5;14(7):1645-9. doi: 10.1016/j.bmcl.2004.01.059. Bioorg Med Chem Lett. 2004. PMID: 15026042
Discovery of a Potent and Orally Bioavailable Dual Antagonist of CC Chemokine Receptors 2 and 5.
Carter PH, Brown GD, Cherney RJ, Batt DG, Chen J, Clark CM, Cvijic ME, Duncia JV, Ko SS, Mandlekar S, Mo R, Nelson DJ, Pang J, Rose AV, Santella JB 3rd, Tebben AJ, Traeger SC, Xu S, Zhao Q, Barrish JC. Carter PH, et al. Among authors: clark cm. ACS Med Chem Lett. 2015 Mar 4;6(4):439-44. doi: 10.1021/ml500505q. eCollection 2015 Apr 9. ACS Med Chem Lett. 2015. PMID: 25893046 Free PMC article.
Choice of antiretroviral therapy has low impact on weight gain.
Drechsler H, Ayers C, Oboho I, Enwerem N, Hanna J, Clark C, Kitchell E, Jain M, Luque A, Bedimo R. Drechsler H, et al. Among authors: clark c. AIDS. 2024 Jun 3. doi: 10.1097/QAD.0000000000003950. Online ahead of print. AIDS. 2024. PMID: 38831733
Technical recommendations for implementation of Volumetric Modulated Arc Therapy and Helical Tomotherapy Total Body Irradiation.
Seravalli E, Bosman ME, Han C, Losert C, Pazos M, Engström PE, Engellau J, Fulcheri CPL, Zucchetti C, Saldi S, Ferrer C, Ocanto A, Hiniker SM, Clark CH, Hussein M, Misson-Yates S, Kobyzeva DA, Loginova AA, Hoeben BAW. Seravalli E, et al. Among authors: clark ch. Radiother Oncol. 2024 Jun 1:110366. doi: 10.1016/j.radonc.2024.110366. Online ahead of print. Radiother Oncol. 2024. PMID: 38830537 Review.
Positive feedbacks and alternative stable states in forest leaf types.
Zou Y, Zohner CM, Averill C, Ma H, Merder J, Berdugo M, Bialic-Murphy L, Mo L, Brun P, Zimmermann NE, Liang J, de-Miguel S, Nabuurs GJ, Reich PB, Niinements U, Dahlgren J, Kändler G, Ratcliffe S, Ruiz-Benito P, de Zavala MA; GFBI consortium; Crowther TW. Zou Y, et al. Nat Commun. 2024 May 31;15(1):4658. doi: 10.1038/s41467-024-48676-5. Nat Commun. 2024. PMID: 38821957 Free PMC article.
Long COVID and cardiovascular disease: a prospective cohort study.
Lawson CA, Moss AJ, Arnold JR, Bagot C, Banerjee A, Berry C, Greenwood J, Hughes AD, Khunti K, Mills NL, Neubauer S, Raman B, Sattar N, Leavy OC, Richardson M, Elneima O, McAuley HJ, Shikotra A, Singapuri A, Sereno M, Saunders R, Harris V, Houchen-Wolloff L, Greening NJ, Harrison E, Docherty AB, Lone NI, Quint JK, Chalmers J, Ho LP, Horsley A, Marks M, Poinasamy K, Evans R, Wain LV, Brightling C, McCann GP; PHOSP-COVID Study Collaborative Group. Lawson CA, et al. Open Heart. 2024 May 27;11(1):e002662. doi: 10.1136/openhrt-2024-002662. Open Heart. 2024. PMID: 38802280 Free PMC article.
5,709 results