Mook OR - Search Results

1

The therapeutic potential of LNA-modified siRNAs: reduction of off-target effects by chemical modification of the siRNA sequence.

Fluiter K, Mook OR, Baas F. Fluiter K, et al. Among authors: mook or. Methods Mol Biol. 2009;487:189-203. doi: 10.1007/978-1-60327-547-7_9. Methods Mol Biol. 2009. PMID: 19301648 Review.

2

Filling the gap in LNA antisense oligo gapmers: the effects of unlocked nucleic acid (UNA) and 4'-C-hydroxymethyl-DNA modifications on RNase H recruitment and efficacy of an LNA gapmer.

Fluiter K, Mook OR, Vreijling J, Langkjaer N, Højland T, Wengel J, Baas F. Fluiter K, et al. Among authors: mook or. Mol Biosyst. 2009 Aug;5(8):838-43. doi: 10.1039/b903922h. Epub 2009 May 19. Mol Biosyst. 2009. PMID: 19603119

3

Allele-specific cancer cell killing in vitro and in vivo targeting a single-nucleotide polymorphism in POLR2A.

Mook OR, Baas F, de Wissel MB, Fluiter K. Mook OR, et al. Cancer Gene Ther. 2009 Jun;16(6):532-8. doi: 10.1038/cgt.2008.104. Epub 2009 Jan 23. Cancer Gene Ther. 2009. PMID: 19165236

4

Evaluation of locked nucleic acid-modified small interfering RNA in vitro and in vivo.

Mook OR, Baas F, de Wissel MB, Fluiter K. Mook OR, et al. Mol Cancer Ther. 2007 Mar;6(3):833-43. doi: 10.1158/1535-7163.MCT-06-0195. Mol Cancer Ther. 2007. PMID: 17363479 Free article.

5

Utilization of unlocked nucleic acid (UNA) to enhance siRNA performance in vitro and in vivo.

Laursen MB, Pakula MM, Gao S, Fluiter K, Mook OR, Baas F, Langklaer N, Wengel SL, Wengel J, Kjems J, Bramsen JB. Laursen MB, et al. Among authors: mook or. Mol Biosyst. 2010 May;6(5):862-70. doi: 10.1039/b918869j. Epub 2010 Feb 9. Mol Biosyst. 2010. PMID: 20567772

6

Targeted sequence capture and GS-FLX Titanium sequencing of 23 hypertrophic and dilated cardiomyopathy genes: implementation into diagnostics.

Mook OR, Haagmans MA, Soucy JF, van de Meerakker JB, Baas F, Jakobs ME, Hofman N, Christiaans I, Lekanne Deprez RH, Mannens MM. Mook OR, et al. J Med Genet. 2013 Sep;50(9):614-26. doi: 10.1136/jmedgenet-2012-101231. Epub 2013 Jun 19. J Med Genet. 2013. PMID: 23785128 Free PMC article.

7

Changes in gene expression of granulocytes during in vivo granulocyte colony-stimulating factor/dexamethasone mobilization for transfusion purposes.

Drewniak A, van Raam BJ, Geissler J, Tool AT, Mook OR, van den Berg TK, Baas F, Kuijpers TW. Drewniak A, et al. Among authors: mook or. Blood. 2009 Jun 4;113(23):5979-98. doi: 10.1182/blood-2008-10-182147. Epub 2009 Apr 6. Blood. 2009. PMID: 19349622 Free article.

8

RELN rare variants in myoclonus-dystonia.

Groen JL, Ritz K, Jalalzadeh H, van der Salm SM, Jongejan A, Mook OR, Haagmans MA, Zwinderman AH, Motazacker MM, Hennekam RC, Baas F, Tijssen MA. Groen JL, et al. Among authors: mook or. Mov Disord. 2015 Mar;30(3):415-9. doi: 10.1002/mds.26070. Epub 2015 Feb 4. Mov Disord. 2015. PMID: 25648840

9

Noninvasive magnetic resonance imaging of the development of individual colon cancer tumors in rat liver.

Mook OR, Jonker A, Strang AC, Veltien A, Gambarota G, Frederiks WM, Heerschap A, Van Noorden CJ. Mook OR, et al. Biotechniques. 2008 Apr;44(4):529-35. doi: 10.2144/000112695. Biotechniques. 2008. PMID: 18476817 Free article.

10

The role of gelatinases in colorectal cancer progression and metastasis.

Mook OR, Frederiks WM, Van Noorden CJ. Mook OR, et al. Biochim Biophys Acta. 2004 Dec 17;1705(2):69-89. doi: 10.1016/j.bbcan.2004.09.006. Biochim Biophys Acta. 2004. PMID: 15588763 Review.

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