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Standardization of WT1 mRNA quantitation for minimal residual disease monitoring in childhood AML and implications of WT1 gene mutations: a European multicenter study.
Willasch AM, Gruhn B, Coliva T, Kalinova M, Schneider G, Kreyenberg H, Steinbach D, Weber G, Hollink IH, Zwaan CM, Biondi A, van der Velden VH, Reinhardt D, Cazzaniga G, Bader P, Trka J; European Study Group on WT1 Expression in Childhood AML. Willasch AM, et al. Leukemia. 2009 Aug;23(8):1472-9. doi: 10.1038/leu.2009.51. Epub 2009 Mar 26. Leukemia. 2009. PMID: 19322206
Children with myelodysplastic syndrome (MDS) and increasing mixed chimaerism after allogeneic stem cell transplantation have a poor outcome which can be improved by pre-emptive immunotherapy.
Bader P, Niemeyer C, Willasch A, Kreyenberg H, Strahm B, Kremens B, Gruhn B, Dilloo D, Vormoor J, Lang P, Niethammer D, Klingebiel T, Beck JF. Bader P, et al. Br J Haematol. 2005 Mar;128(5):649-58. doi: 10.1111/j.1365-2141.2004.05354.x. Br J Haematol. 2005. PMID: 15725087 Free article. Clinical Trial.
Sequence polymorphism systems for quantitative real-time polymerase chain reaction to characterize hematopoietic chimerism-high informativity and sensitivity as well as excellent reproducibility and precision of measurement.
Willasch A, Schneider G, Reincke BS, Shayegi N, Kreyenberg H, Kuci S, Weber G, Van Der Reijden B, Niethammer D, Klingebiel T, Bader P. Willasch A, et al. Lab Hematol. 2007;13(3):73-84. doi: 10.1532/LH96.07004. Lab Hematol. 2007. PMID: 17984038
Prognostic value of minimal residual disease quantification before allogeneic stem-cell transplantation in relapsed childhood acute lymphoblastic leukemia: the ALL-REZ BFM Study Group.
Bader P, Kreyenberg H, Henze GH, Eckert C, Reising M, Willasch A, Barth A, Borkhardt A, Peters C, Handgretinger R, Sykora KW, Holter W, Kabisch H, Klingebiel T, von Stackelberg A; ALL-REZ BFM Study Group. Bader P, et al. J Clin Oncol. 2009 Jan 20;27(3):377-84. doi: 10.1200/JCO.2008.17.6065. Epub 2008 Dec 8. J Clin Oncol. 2009. PMID: 19064980
Clinical relevance of Wilms tumor 1 gene mutations in childhood acute myeloid leukemia.
Hollink IH, van den Heuvel-Eibrink MM, Zimmermann M, Balgobind BV, Arentsen-Peters ST, Alders M, Willasch A, Kaspers GJ, Trka J, Baruchel A, de Graaf SS, Creutzig U, Pieters R, Reinhardt D, Zwaan CM. Hollink IH, et al. Blood. 2009 Jun 4;113(23):5951-60. doi: 10.1182/blood-2008-09-177949. Epub 2009 Jan 26. Blood. 2009. PMID: 19171881 Free article.
Immunoglobulin and T-cell receptor gene rearrangements as PCR-based targets are stable markers for monitoring minimal residual disease in acute lymphoblastic leukemia after stem cell transplantation.
Kreyenberg H, Eckert C, Yarkin Y, Reising M, Willasch A, Handgretinger R, Kremens B, von Stackelberg A, Henze G, Klingebiel T, Bader P. Kreyenberg H, et al. Leukemia. 2009 Jul;23(7):1355-8. doi: 10.1038/leu.2009.72. Epub 2009 Apr 9. Leukemia. 2009. PMID: 19357703 No abstract available.
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