Paulson MS - Search Results

1

Comparison of HCV NS3 protease and NS5B polymerase inhibitor activity in 1a, 1b and 2a replicons and 2a infectious virus.

Paulson MS, Yang H, Shih IH, Feng JY, Mabery EM, Robinson MF, Zhong W, Delaney WE 4th. Paulson MS, et al. Antiviral Res. 2009 Aug;83(2):135-42. doi: 10.1016/j.antiviral.2009.04.003. Epub 2009 Apr 14. Antiviral Res. 2009. PMID: 19457562

2

A small-molecule inhibitor of hepatitis C virus infectivity.

Bush CO, Pokrovskii MV, Saito R, Morganelli P, Canales E, Clarke MO, Lazerwith SE, Golde J, Reid BG, Babaoglu K, Pagratis N, Zhong W, Delaney WE 4th, Paulson MS, Beran RK. Bush CO, et al. Among authors: paulson ms. Antimicrob Agents Chemother. 2014;58(1):386-96. doi: 10.1128/AAC.02083-13. Epub 2013 Oct 28. Antimicrob Agents Chemother. 2014. PMID: 24165192 Free PMC article.

3

Mechanistic characterization of GS-9190 (Tegobuvir), a novel nonnucleoside inhibitor of hepatitis C virus NS5B polymerase.

Shih IH, Vliegen I, Peng B, Yang H, Hebner C, Paeshuyse J, Pürstinger G, Fenaux M, Tian Y, Mabery E, Qi X, Bahador G, Paulson M, Lehman LS, Bondy S, Tse W, Reiser H, Lee WA, Schmitz U, Neyts J, Zhong W. Shih IH, et al. Antimicrob Agents Chemother. 2011 Sep;55(9):4196-203. doi: 10.1128/AAC.00307-11. Epub 2011 Jul 11. Antimicrob Agents Chemother. 2011. PMID: 21746939 Free PMC article.

4

Selection of clinically relevant protease inhibitor-resistant viruses using the genotype 2a hepatitis C virus infection system.

Cheng G, Chan K, Yang H, Corsa A, Pokrovskii M, Paulson M, Bahador G, Zhong W, Delaney W 4th. Cheng G, et al. Antimicrob Agents Chemother. 2011 May;55(5):2197-205. doi: 10.1128/AAC.01382-10. Epub 2011 Feb 28. Antimicrob Agents Chemother. 2011. PMID: 21357305 Free PMC article.

5

Novel mutations in a tissue culture-adapted hepatitis C virus strain improve infectious-virus stability and markedly enhance infection kinetics.

Pokrovskii MV, Bush CO, Beran RK, Robinson MF, Cheng G, Tirunagari N, Fenaux M, Greenstein AE, Zhong W, Delaney WE 4th, Paulson MS. Pokrovskii MV, et al. Among authors: paulson ms. J Virol. 2011 Apr;85(8):3978-85. doi: 10.1128/JVI.01760-10. Epub 2011 Feb 2. J Virol. 2011. PMID: 21289124 Free PMC article.

6

Substituted imidazopyridines as potent inhibitors of HCV replication.

Vliegen I, Paeshuyse J, De Burghgraeve T, Lehman LS, Paulson M, Shih IH, Mabery E, Boddeker N, De Clercq E, Reiser H, Oare D, Lee WA, Zhong W, Bondy S, Pürstinger G, Neyts J. Vliegen I, et al. J Hepatol. 2009 May;50(5):999-1009. doi: 10.1016/j.jhep.2008.12.028. Epub 2009 Feb 26. J Hepatol. 2009. PMID: 19303654 Free PMC article.

7

Generation and quantitation of infectious hepatitis C virus derived from cell culture (HCVcc).

Paulson MS. Paulson MS. Curr Protoc Pharmacol. 2010 Dec;Chapter 13:Unit 13B.4. doi: 10.1002/0471141755.ph13b04s51. Curr Protoc Pharmacol. 2010. PMID: 21935897

8

Genome-wide association study to characterize serum bilirubin elevations in patients with HCV treated with GS-9256, an HCV NS3 serine protease inhibitor.

Nelson D, Yoshida EM, Paulson MS, Hengen PN, Ge D, Kanwar B, McNally J, Pang PS, Subramanian GM, McHutchison JG, Urbanek P, Lawitz E, Urban TJ. Nelson D, et al. Among authors: paulson ms. Antivir Ther. 2014;19(7):679-86. doi: 10.3851/IMP2747. Epub 2014 Feb 6. Antivir Ther. 2014. PMID: 24503447

9

Temporal dynamics of inflammatory cytokines/chemokines during sofosbuvir and ribavirin therapy for genotype 2 and 3 hepatitis C infection.

Carlin AF, Aristizabal P, Song Q, Wang H, Paulson MS, Stamm LM, Schooley RT, Wyles DL. Carlin AF, et al. Among authors: paulson ms. Hepatology. 2015 Oct;62(4):1047-58. doi: 10.1002/hep.27971. Epub 2015 Aug 22. Hepatology. 2015. PMID: 26147061 Free PMC article.

10

Dysregulation of distal cholesterol biosynthesis in association with relapse and advanced disease in CHC genotype 2 and 3 treated with sofosbuvir and ribavirin.

Younossi ZM, Stepanova M, Estep M, Negro F, Clark PJ, Hunt S, Song Q, Paulson M, Stamm LM, Brainard DM, Subramanian GM, McHutchison JG, Patel K. Younossi ZM, et al. J Hepatol. 2016 Jan;64(1):29-36. doi: 10.1016/j.jhep.2015.08.027. Epub 2015 Sep 1. J Hepatol. 2016. PMID: 26341824

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