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Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment.
Mathews RJ, Robinson JI, Battellino M, Wong C, Taylor JC; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate (BRAGGSS); Eyre S, Churchman SM, Wilson AG, Isaacs JD, Hyrich K, Barton A, Plant D, Savic S, Cook GP, Sarzi-Puttini P, Emery P, Barrett JH, Morgan AW, McDermott MF. Mathews RJ, et al. Among authors: mcdermott mf. Ann Rheum Dis. 2014 Jun;73(6):1202-10. doi: 10.1136/annrheumdis-2013-203276. Epub 2013 May 17. Ann Rheum Dis. 2014. PMID: 23687262
Inositol-Requiring Enzyme 1-Mediated Downregulation of MicroRNA (miR)-146a and miR-155 in Primary Dermal Fibroblasts across Three TNFRSF1A Mutations Results in Hyperresponsiveness to Lipopolysaccharide.
Harrison SR, Scambler T, Oubussad L, Wong C, Wittmann M, McDermott MF, Savic S. Harrison SR, et al. Among authors: mcdermott mf. Front Immunol. 2018 Feb 6;9:173. doi: 10.3389/fimmu.2018.00173. eCollection 2018. Front Immunol. 2018. PMID: 29467762 Free PMC article.
Autoinflammatory disease in the lung.
Scambler T, Holbrook J, Savic S, McDermott MF, Peckham D. Scambler T, et al. Among authors: mcdermott mf. Immunology. 2018 Apr 19;154(4):563-73. doi: 10.1111/imm.12937. Online ahead of print. Immunology. 2018. PMID: 29676014 Free PMC article. Review.
TNF receptor signalling in autoinflammatory diseases.
Jarosz-Griffiths HH, Holbrook J, Lara-Reyna S, McDermott MF. Jarosz-Griffiths HH, et al. Among authors: mcdermott mf. Int Immunol. 2019 Sep 18;31(10):639-648. doi: 10.1093/intimm/dxz024. Int Immunol. 2019. PMID: 30838383 Free article. Review.
153 results