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534 results

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Potent and selective agonism of the melanocortin receptor 4 with MK-0493 does not induce weight loss in obese human subjects: energy intake predicts lack of weight loss efficacy.
Krishna R, Gumbiner B, Stevens C, Musser B, Mallick M, Suryawanshi S, Maganti L, Zhu H, Han TH, Scherer L, Simpson B, Cosgrove D, Gottesdiener K, Amatruda J, Rolls BJ, Blundell J, Bray GA, Fujioka K, Heymsfield SB, Wagner JA, Herman GA. Krishna R, et al. Among authors: blundell j. Clin Pharmacol Ther. 2009 Dec;86(6):659-66. doi: 10.1038/clpt.2009.167. Epub 2009 Sep 9. Clin Pharmacol Ther. 2009. PMID: 19741604 Clinical Trial.
The acyclic CB1R inverse agonist taranabant mediates weight loss by increasing energy expenditure and decreasing caloric intake.
Addy C, Wright H, Van Laere K, Gantz I, Erondu N, Musser BJ, Lu K, Yuan J, Sanabria-Bohórquez SM, Stoch A, Stevens C, Fong TM, De Lepeleire I, Cilissen C, Cote J, Rosko K, Gendrano IN 3rd, Nguyen AM, Gumbiner B, Rothenberg P, de Hoon J, Bormans G, Depré M, Eng WS, Ravussin E, Klein S, Blundell J, Herman GA, Burns HD, Hargreaves RJ, Wagner J, Gottesdiener K, Amatruda JM, Heymsfield SB. Addy C, et al. Among authors: blundell j. Cell Metab. 2008 Jan;7(1):68-78. doi: 10.1016/j.cmet.2007.11.012. Cell Metab. 2008. PMID: 18177726 Free article. Clinical Trial.
The case of GWAS of obesity: does body weight control play by the rules?
Müller MJ, Geisler C, Blundell J, Dulloo A, Schutz Y, Krawczak M, Bosy-Westphal A, Enderle J, Heymsfield SB. Müller MJ, et al. Among authors: blundell j. Int J Obes (Lond). 2018 Aug;42(8):1395-1405. doi: 10.1038/s41366-018-0081-6. Epub 2018 May 24. Int J Obes (Lond). 2018. PMID: 29795468 Free article. Review.
Pramlintide treatment reduces 24-h caloric intake and meal sizes and improves control of eating in obese subjects: a 6-wk translational research study.
Smith SR, Blundell JE, Burns C, Ellero C, Schroeder BE, Kesty NC, Chen KS, Halseth AE, Lush CW, Weyer C. Smith SR, et al. Am J Physiol Endocrinol Metab. 2007 Aug;293(2):E620-7. doi: 10.1152/ajpendo.00217.2007. Epub 2007 May 15. Am J Physiol Endocrinol Metab. 2007. PMID: 17505051 Free article. Clinical Trial.
534 results