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Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling.
Huang SM, Mishina YM, Liu S, Cheung A, Stegmeier F, Michaud GA, Charlat O, Wiellette E, Zhang Y, Wiessner S, Hild M, Shi X, Wilson CJ, Mickanin C, Myer V, Fazal A, Tomlinson R, Serluca F, Shao W, Cheng H, Shultz M, Rau C, Schirle M, Schlegl J, Ghidelli S, Fawell S, Lu C, Curtis D, Kirschner MW, Lengauer C, Finan PM, Tallarico JA, Bouwmeester T, Porter JA, Bauer A, Cong F. Huang SM, et al. Among authors: wiellette e. Nature. 2009 Oct 1;461(7264):614-20. doi: 10.1038/nature08356. Epub 2009 Sep 16. Nature. 2009. PMID: 19759537
Zebrafish promoter microarrays identify actively transcribed embryonic genes.
Wardle FC, Odom DT, Bell GW, Yuan B, Danford TW, Wiellette EL, Herbolsheimer E, Sive HL, Young RA, Smith JC. Wardle FC, et al. Among authors: wiellette el. Genome Biol. 2006;7(8):R71. doi: 10.1186/gb-2006-7-8-R71. Epub 2006 Aug 4. Genome Biol. 2006. PMID: 16889661 Free PMC article.
A platform to reproducibly evaluate human colon permeability and damage.
Marr EE, Mulhern TJ, Welch M, Keegan P, Caballero-Franco C, Johnson BG, Kasaian M, Azizgolshani H, Petrie T, Charest J, Wiellette E. Marr EE, et al. Among authors: wiellette e. Sci Rep. 2023 Jun 1;13(1):8922. doi: 10.1038/s41598-023-36020-8. Sci Rep. 2023. PMID: 37264117 Free PMC article.
High-throughput organ-on-chip platform with integrated programmable fluid flow and real-time sensing for complex tissue models in drug development workflows.
Azizgolshani H, Coppeta JR, Vedula EM, Marr EE, Cain BP, Luu RJ, Lech MP, Kann SH, Mulhern TJ, Tandon V, Tan K, Haroutunian NJ, Keegan P, Rogers M, Gard AL, Baldwin KB, de Souza JC, Hoefler BC, Bale SS, Kratchman LB, Zorn A, Patterson A, Kim ES, Petrie TA, Wiellette EL, Williams C, Isenberg BC, Charest JL. Azizgolshani H, et al. Among authors: wiellette el. Lab Chip. 2021 Apr 20;21(8):1454-1474. doi: 10.1039/d1lc00067e. Lab Chip. 2021. PMID: 33881130